Antiplatelet and Anticoagulant Pharmacology for the Laboratory Professional test questions

Antiplatelet and
Anticoagulant Pharmacology
for the Laboratory
Professional test questions
and answers
a.Protein C
b.Tissue factor
c.Thromboxane A2
d.Antithrombin III
e.Plasmin
a.<strong>Inhibitors</strong> of Coagulation
b.<strong>Promoters</strong> of Coagulation\
c.<strong>Promoters</strong> of Coagulation
d.<strong>Inhibitors</strong> of Coagulation
e.<strong>Inhibitors</strong> of Coagulation
Which nonsteroidal anti-inflammatory drugs (NSAIDs) produce an
irreversible inhibition of platelets, making it the preferred therapy in
patients who have had heart attacks and strokes or may have a heart
attack or stroke?
Aspirin irreversibly inhibits the enzyme COX, leading to decreased
production of thromboxane A2 and decreased platelet aggregation. Since
platelets do not have a nucleus, they do not have the means of producing
more COX enzyme to overcome the effects of aspirin. Thus, aspirin inhibits
platelets for the remainder of their life span, which could be up to ten
days.
Brainpower
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