MCPHS Psychopharmacology Quiz 3
Lecturez1:zCancerz-zCORRECTzANSWER-
Cisplatinz-zCORRECTzANSWER-chemozdrug
Methotrexatez-zCORRECTzANSWER-chemozdrug
Tamoxifenz-zCORRECTzANSWER-chemozdrug
Vincristinez-zCORRECTzANSWER-chemozdrug
Cyclosporinez-zCORRECTzANSWER-chemozdrug
Epoetinzalfaz(Epogen,zProcrit)z-zCORRECTzANSWER-treatszanemiaz
usedzforzcancerzpatients
Neulastaz-zCORRECTzANSWER-colonyzstimulatingzfactors
decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients
Neupogenz-zCORRECTzANSWER-colonyzstimulatingzfactors
decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients
Dronabinolz(Marinol)z-zCORRECTzANSWER-
Cannabinoidzgivenz*afterzchemo*zforzCINVzandzaszanzappetitezstimulant
Canzcausezdissociation/dysphoria,zhypotension,ztachycardia
,Megestrolzacetatez*(Megace)*z-zCORRECTzANSWER-
N&Vzmedication;zazprogestinzthatzactszaszanzappetitezstimulant,z*not*zappropriatezforzptszwithzprostatezc
ancerzorzptszwithzhyperglycemia
Ondansetronz(Zofran)z-zCORRECTzANSWER-
antiemeticzgivenz*before*zadministrationzofzchemotherapyztozpreventzCINV
Dexamethasonez-zCORRECTzANSWER-steroidzcanzgivenz*beforezorzafter*zadministrationzofzchemotherapy
Cisplatinzleadsztoz______ztoxicitiyz-zCORRECTzANSWER-renal
Bleomycinzleadsztoz_______ztoxicityz-zCORRECTzANSWER-lung
Doxorubicin/daunorubicinzleadsztoz______ztoxicityz-zCORRECTzANSWER-cardio
Vincristinezleadsztoz_______ztoxicityz-zCORRECTzANSWER-neuro
Methotrexatezleadsztoz_______ztoxicityz-zCORRECTzANSWER-hepato
Activityzrestrictionszforzneuropathyzinzcancerzptsz-zCORRECTzANSWER-avoidztreadmill
Activityzrestrictionszforzosteoporosiszorzbonezmetastaseszinzcancerzptsz-zCORRECTzANSWER-
avoidzhighzimpactzexercise
Activityzrestrictionszforzneutropeniazinzcancerzptsz-zCORRECTzANSWER-avoidzswimming
Activityzrestrictionszforzmusclezwastingzinzcancerzptsz-zCORRECTzANSWER-
limitzresistiveztrainingztozveryzlightzweight
Activityzrestrictionszforzcardiotoxiczchemozinzcancerzptsz-zCORRECTzANSWER-
mayzrequirezcardiaczmonitoring
, Activityzrestrictionszforzanemiazinzcancerzptsz-zCORRECTzANSWER-fatigue
Activityzrestrictionszforzthrombocytopeniazinzcancerzptsz-zCORRECTzANSWER-avoidzimpactztraining
Whatziszthezmostzcommonzdosezlimitingztoxicityzinzchemotherapy?z-zCORRECTzANSWER-
bonezmarrowzsuppression
Thrombocytopeniaz-zCORRECTzANSWER-lowzplateletzcount
Thezlowerzthezplateletzcountzthezhigherzthezbleedingzrisk
Extremelyzlowzplateletzcountszlimitzpatients'
physicalzactivityzespzifz<50,000/mm3
Neutropeniaz-zCORRECTzANSWER-azdecreasedznumberzofzneutrophilsz(<1500/mm3)
Absolutezneutrophilzcountz(ANC)zmeasureszinfectionzsusceptibility
↓neutrophilzcountz↑riskzofzinfection
Colonyzstimulatingzfactorsz-zCORRECTzANSWER-•zTypicallyzusedztozspeedzrecoveryzfrom
myelosuppressivezchemotherapy
•zStimulatezgrowthzofznewzwhitezbloodzcells
Lecturez2:zAnesthesiaz-zCORRECTzANSWER-
Whatziszspasticity?z-zCORRECTzANSWER-
Increasedzmuscleztonezdueztozresistancezofzpassivezmovementzofzlimb
Followedzbyzsuddenzrelaxationz
Lecturez1:zCancerz-zCORRECTzANSWER-
Cisplatinz-zCORRECTzANSWER-chemozdrug
Methotrexatez-zCORRECTzANSWER-chemozdrug
Tamoxifenz-zCORRECTzANSWER-chemozdrug
Vincristinez-zCORRECTzANSWER-chemozdrug
Cyclosporinez-zCORRECTzANSWER-chemozdrug
Epoetinzalfaz(Epogen,zProcrit)z-zCORRECTzANSWER-treatszanemiaz
usedzforzcancerzpatients
Neulastaz-zCORRECTzANSWER-colonyzstimulatingzfactors
decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients
Neupogenz-zCORRECTzANSWER-colonyzstimulatingzfactors
decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients
Dronabinolz(Marinol)z-zCORRECTzANSWER-
Cannabinoidzgivenz*afterzchemo*zforzCINVzandzaszanzappetitezstimulant
Canzcausezdissociation/dysphoria,zhypotension,ztachycardia
,Megestrolzacetatez*(Megace)*z-zCORRECTzANSWER-
N&Vzmedication;zazprogestinzthatzactszaszanzappetitezstimulant,z*not*zappropriatezforzptszwithzprostatezc
ancerzorzptszwithzhyperglycemia
Ondansetronz(Zofran)z-zCORRECTzANSWER-
antiemeticzgivenz*before*zadministrationzofzchemotherapyztozpreventzCINV
Dexamethasonez-zCORRECTzANSWER-steroidzcanzgivenz*beforezorzafter*zadministrationzofzchemotherapy
Cisplatinzleadsztoz______ztoxicitiyz-zCORRECTzANSWER-renal
Bleomycinzleadsztoz_______ztoxicityz-zCORRECTzANSWER-lung
Doxorubicin/daunorubicinzleadsztoz______ztoxicityz-zCORRECTzANSWER-cardio
Vincristinezleadsztoz_______ztoxicityz-zCORRECTzANSWER-neuro
Methotrexatezleadsztoz_______ztoxicityz-zCORRECTzANSWER-hepato
Activityzrestrictionszforzneuropathyzinzcancerzptsz-zCORRECTzANSWER-avoidztreadmill
Activityzrestrictionszforzosteoporosiszorzbonezmetastaseszinzcancerzptsz-zCORRECTzANSWER-
avoidzhighzimpactzexercise
Activityzrestrictionszforzneutropeniazinzcancerzptsz-zCORRECTzANSWER-avoidzswimming
Activityzrestrictionszforzmusclezwastingzinzcancerzptsz-zCORRECTzANSWER-
limitzresistiveztrainingztozveryzlightzweight
Activityzrestrictionszforzcardiotoxiczchemozinzcancerzptsz-zCORRECTzANSWER-
mayzrequirezcardiaczmonitoring
, Activityzrestrictionszforzanemiazinzcancerzptsz-zCORRECTzANSWER-fatigue
Activityzrestrictionszforzthrombocytopeniazinzcancerzptsz-zCORRECTzANSWER-avoidzimpactztraining
Whatziszthezmostzcommonzdosezlimitingztoxicityzinzchemotherapy?z-zCORRECTzANSWER-
bonezmarrowzsuppression
Thrombocytopeniaz-zCORRECTzANSWER-lowzplateletzcount
Thezlowerzthezplateletzcountzthezhigherzthezbleedingzrisk
Extremelyzlowzplateletzcountszlimitzpatients'
physicalzactivityzespzifz<50,000/mm3
Neutropeniaz-zCORRECTzANSWER-azdecreasedznumberzofzneutrophilsz(<1500/mm3)
Absolutezneutrophilzcountz(ANC)zmeasureszinfectionzsusceptibility
↓neutrophilzcountz↑riskzofzinfection
Colonyzstimulatingzfactorsz-zCORRECTzANSWER-•zTypicallyzusedztozspeedzrecoveryzfrom
myelosuppressivezchemotherapy
•zStimulatezgrowthzofznewzwhitezbloodzcells
Lecturez2:zAnesthesiaz-zCORRECTzANSWER-
Whatziszspasticity?z-zCORRECTzANSWER-
Increasedzmuscleztonezdueztozresistancezofzpassivezmovementzofzlimb
Followedzbyzsuddenzrelaxationz
