ACTIVE LEARNING TEMPLATE: Medication
Kelly Gonzalez
STUDENT NAME _____________________________________
pantoprazole (Protonix) others: prilosec (Omeprazole); lansoprazole (Prevacid)
MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________
Proton-Pump Inhibitors (PPIs)/Benzimidazole
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
*reduces gastric acid by increasing pH * tx for esophagitis, GERD, duodenal ulcer, hypersecretory
conditions (benign gastric ulcer). otc: heartburn
through inhibition of the enzyme, H+/K+ *Off-label: Prevention/tx of NSAID-induced ulcers, stress
adenosine triphosphatase pump ulcer prophylaxis in critically ill pts.
Complications Medication Administration
*Pancreatitis, hepatotoxicity, interstitial *PO: delayed release (10, 20,
nephritis occur rarely. May increase risk of C. difficile 40 mg), suspension (2.5 mg or
infection. 10 mg packet)
*onset: 1hr, peak: 2hr, duration:
72hr
*no dose adjustment for renal/
hepatic impairment
Contraindications/Precautions
*contraindicated: hypersensitivity to PPIs or concurrent
use with rilpivirine
*cautions: increase risk of fractures, GI infections, hepatic Nursing Interventions
impairment to pts of Asian descent, elderly *assess/monitor VS
*assess for GI discomfort,
nausea, and diarrhea
*monitor lab values: may
increase serum alkaline
Interactions phosphatase, ALT, AST
*May decrease effects: clopidogrel, cefuroxime
*May increase effects: oral anticogulants (warfarin),
phenytoin, escitalopram, voriconazole
*Herbals that decrease effects: St. John's wort
Client Education
*avoid alcohol
*take prior to eating
Evaluation of Medication Effectiveness *do not chew
*relief of GI symptoms capsules/cut/dissolve
*report dizziness, asthenia,
rash, cough, onset of black,
tarry stools, diarrhea, abdominal
pain
ACTIVE LEARNING TEMPLATES THERAPEUTIC PROCEDURE A7
Kelly Gonzalez
STUDENT NAME _____________________________________
pantoprazole (Protonix) others: prilosec (Omeprazole); lansoprazole (Prevacid)
MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________
Proton-Pump Inhibitors (PPIs)/Benzimidazole
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
*reduces gastric acid by increasing pH * tx for esophagitis, GERD, duodenal ulcer, hypersecretory
conditions (benign gastric ulcer). otc: heartburn
through inhibition of the enzyme, H+/K+ *Off-label: Prevention/tx of NSAID-induced ulcers, stress
adenosine triphosphatase pump ulcer prophylaxis in critically ill pts.
Complications Medication Administration
*Pancreatitis, hepatotoxicity, interstitial *PO: delayed release (10, 20,
nephritis occur rarely. May increase risk of C. difficile 40 mg), suspension (2.5 mg or
infection. 10 mg packet)
*onset: 1hr, peak: 2hr, duration:
72hr
*no dose adjustment for renal/
hepatic impairment
Contraindications/Precautions
*contraindicated: hypersensitivity to PPIs or concurrent
use with rilpivirine
*cautions: increase risk of fractures, GI infections, hepatic Nursing Interventions
impairment to pts of Asian descent, elderly *assess/monitor VS
*assess for GI discomfort,
nausea, and diarrhea
*monitor lab values: may
increase serum alkaline
Interactions phosphatase, ALT, AST
*May decrease effects: clopidogrel, cefuroxime
*May increase effects: oral anticogulants (warfarin),
phenytoin, escitalopram, voriconazole
*Herbals that decrease effects: St. John's wort
Client Education
*avoid alcohol
*take prior to eating
Evaluation of Medication Effectiveness *do not chew
*relief of GI symptoms capsules/cut/dissolve
*report dizziness, asthenia,
rash, cough, onset of black,
tarry stools, diarrhea, abdominal
pain
ACTIVE LEARNING TEMPLATES THERAPEUTIC PROCEDURE A7
