NR 508 ADVANCED PHARMACOLOGY 2023 FINAL 3 LATEST
VERSIONS EACH VERSION WITH 75 QUESTIONS AND CORRECT
ANSWERS
State the three (3) most important characteristics of any drug. - ANSWER:
effectiveness, safety, selectivity
Is it possible to have a selective drug? - ANSWER: No, all medications have side
effects
Define the four phases of pharmacokenetics. - ANSWER: Absorption, distribution,
metabolism and excretion
Define pharmacodynamics. - ANSWER: The nature and intensity of the response the
drug has on the body
Name the three most important goals of pre-administration assessment. - ANSWER:
Evaluate effects, identify high risk patients, and assess for self care
What factors can predispose an individual to adverse reactions from drugs? -
ANSWER: Allergies, pregnancy, age, genetics and pathological disease (kidney or
liver)
What measures help reduce adverse reactions of medication administration? -
ANSWER: A thorough patient history to identify those who might be high risk and
education
What type of research is required to assess drug therapies? - ANSWER: A
randomized control trial is required for all new medications
What is a "blinded" study? - ANSWER: Participants don't know if they belong to the
control or experimental group
Which Amendment strengthened drug regulation after the Thalidomide tragedy in
Europe? - ANSWER: Harris-Kefauver Amendment to the FDA and the Cosmetic act of
1962
What is the purpose of having a trade name (proprietary or brand name) for a drug?
- ANSWER: Trade names are easy to recall and pronounce, and good for marketing
purposes
What is one of the problems with trade names? - ANSWER: Using two brand name
drugs that have the same ingredient can lead to overdose
Binds and blocks peptidases? - ANSWER: Penicillin's
, commonly used to treat urinary tract infections? - ANSWER: Floroquinolones
inhibits cell wall synthesis - ANSWER: Cephalosporins
prevents translocation - ANSWER: Macrolides
Beta Lactam ring - ANSWER: Penicillin
inhibits folic acid synthesis - ANSWER: Sulfonomides
Has a disulfiram like reaction when taken with alcohol - ANSWER: Cephalosporins
Gram positive - ANSWER: Macrolides
causes prolonged QT interval - ANSWER: Flouroquinolones
Causes GI upset, hepatotoxicity, flatulence, jaundice, anorexia and adverse effects -
ANSWER: Macrolides
Causes teeth discoloration - ANSWER: Tetracycline
Associated with spontaneous tendon rupture - ANSWER: Floroquinolones
Inhibits the process of translation - ANSWER: Aminoglycosides
inhibits DNA gyrase - ANSWER: Floroquinolones
Broad spectrum change shape of 30s sub unit - ANSWER: Amnioglycosides
inhibits cell wall production - ANSWER: Penicillin
interferes with tRNA attachment - ANSWER: Tetracycline
most common antibiotic to be allergic to - ANSWER: Sulfonomides
inhibits protein synthesis - ANSWER: Aminoglycosides
The study of drugs and their actions on the body - ANSWER: Pharmacology
The first part of the drug development process
Identification of promising drugs and testing on animals occurs in this phase -
ANSWER: Pre clinical Stage
quantal and graded - ANSWER: Two types of drug responses
VERSIONS EACH VERSION WITH 75 QUESTIONS AND CORRECT
ANSWERS
State the three (3) most important characteristics of any drug. - ANSWER:
effectiveness, safety, selectivity
Is it possible to have a selective drug? - ANSWER: No, all medications have side
effects
Define the four phases of pharmacokenetics. - ANSWER: Absorption, distribution,
metabolism and excretion
Define pharmacodynamics. - ANSWER: The nature and intensity of the response the
drug has on the body
Name the three most important goals of pre-administration assessment. - ANSWER:
Evaluate effects, identify high risk patients, and assess for self care
What factors can predispose an individual to adverse reactions from drugs? -
ANSWER: Allergies, pregnancy, age, genetics and pathological disease (kidney or
liver)
What measures help reduce adverse reactions of medication administration? -
ANSWER: A thorough patient history to identify those who might be high risk and
education
What type of research is required to assess drug therapies? - ANSWER: A
randomized control trial is required for all new medications
What is a "blinded" study? - ANSWER: Participants don't know if they belong to the
control or experimental group
Which Amendment strengthened drug regulation after the Thalidomide tragedy in
Europe? - ANSWER: Harris-Kefauver Amendment to the FDA and the Cosmetic act of
1962
What is the purpose of having a trade name (proprietary or brand name) for a drug?
- ANSWER: Trade names are easy to recall and pronounce, and good for marketing
purposes
What is one of the problems with trade names? - ANSWER: Using two brand name
drugs that have the same ingredient can lead to overdose
Binds and blocks peptidases? - ANSWER: Penicillin's
, commonly used to treat urinary tract infections? - ANSWER: Floroquinolones
inhibits cell wall synthesis - ANSWER: Cephalosporins
prevents translocation - ANSWER: Macrolides
Beta Lactam ring - ANSWER: Penicillin
inhibits folic acid synthesis - ANSWER: Sulfonomides
Has a disulfiram like reaction when taken with alcohol - ANSWER: Cephalosporins
Gram positive - ANSWER: Macrolides
causes prolonged QT interval - ANSWER: Flouroquinolones
Causes GI upset, hepatotoxicity, flatulence, jaundice, anorexia and adverse effects -
ANSWER: Macrolides
Causes teeth discoloration - ANSWER: Tetracycline
Associated with spontaneous tendon rupture - ANSWER: Floroquinolones
Inhibits the process of translation - ANSWER: Aminoglycosides
inhibits DNA gyrase - ANSWER: Floroquinolones
Broad spectrum change shape of 30s sub unit - ANSWER: Amnioglycosides
inhibits cell wall production - ANSWER: Penicillin
interferes with tRNA attachment - ANSWER: Tetracycline
most common antibiotic to be allergic to - ANSWER: Sulfonomides
inhibits protein synthesis - ANSWER: Aminoglycosides
The study of drugs and their actions on the body - ANSWER: Pharmacology
The first part of the drug development process
Identification of promising drugs and testing on animals occurs in this phase -
ANSWER: Pre clinical Stage
quantal and graded - ANSWER: Two types of drug responses
