CHEMO CERTIFICATION TEST LATEST 2024 EXAM WITH
QUESTIONS AND CORRECT ANSWERS
What drug classification is Ixabepilone (Ixempra)?
A. Antimetabolities
B. Misc.
C. Plant Alkaloids - ANSWER>>B
What is a normal hgb? - ANSWER>>14-18 for men
12-16 for women
Where are the most common areas of metastasis? - ANSWER>>Bone, liver, lung, brain
What is maturation/differentiation? - ANSWER>>How well the tumor cell match the
original cells
What is proliferation/division? - ANSWER>>How quickly the cells is dividing
What are the pros and cons to rapid proliferation? - ANSWER>>Pros: you can hit this
Ca. hard with the treat meant and it will respond well
Con: It can divide to fast for treatment to work
What are the pros and cons of slow proliferation? - ANSWER>>Pro: You can watch and
wait because you don't need treatment right away
Cons: Can swing to fast proliferation easily and you don't start treatment right away
,Tell me about
Grade 1 differentiation - ANSWER>>Well differentiated
Confined to organ of origin
Looks like the original cell that it comes from
70-90% survival rate
Tell me about
Grade 2 Differentiation - ANSWER>>Moderately differentiated
Local spread with close nodal involvement
45-55% survival rate
Tell me about
Grade 3 differentiation - ANSWER>>tumor fixed with extensive nodal involvement
25% survival rate
Tell me about
Grade 4 Differentiation - ANSWER>>Mets to other organs and tissues
cannot tell where the cell originated from
<5% survival rate
The Vinca Alkaloids have which dose-limiting toxicity? - ANSWER>>Neuro-toxicity
What are some examples of how you assess for neurotoxicity? - ANSWER>>Sensation
,Ability to button a shirt
Any tingling
Eye droop
Fine motor movements
Tingling
Balance
Attention span
Concentration
Etoposide (VP-16) has this known side effect with rapid transfusion -
ANSWER>>Hypotension
When administering taxanes, what is the total bilirubin requirement? - ANSWER>><1.2
Capecitabine (Xeloda) should not be taken with what medication and why? -
ANSWER>>Warfarin and coumadin
It increases the chance of have toxic levels of these drugs
What dose-limiting toxicity does Capecitabine (Xeloda) have? - ANSWER>>Palmar-
Plantar erythrodysesthesia (PPE)
When administering Fluorouracil (5FU) which toxicity is noted most in...
IVP
IV Infusion - ANSWER>>IVP-Myelosupression
, IV Infusion- GI symptoms
What foods do you avoid when taking Procarbazine?
What are some examples? - ANSWER>>Tyramine
Ex: Cheese, alcohol, cured meats, smoke fish
This metabolite drug requires vigorous hydration, dexamthasone, anti-emetics, and
folic acid? - ANSWER>>Pemetrexed (Alimta)
Where are the most common sites of metastasis? - ANSWER>>Bone, Brain, Liver, Lung
How do you treat an extravasation of an Anti-tumor antibiotic Anthracyclines? -
ANSWER>>Stop the infusion immediately and put a cold compress on the site
What is the total dose you can have of Doxorubcin? - ANSWER>><450-550mg/m^2
What is adjuvant therapy? - ANSWER>>Prophylactic treatment
Chemo after surgery
Surgery is primary treatment
What is neo-adjuvant therapy? - ANSWER>>Administer chemo prior to surgery to
shrink the tumor
What is chemotherapy? - ANSWER>>Cytotoxic drugs that destroy cancer cells or
prevent cellular replication by interfering with DNA and RNA and vital cellular proteins
QUESTIONS AND CORRECT ANSWERS
What drug classification is Ixabepilone (Ixempra)?
A. Antimetabolities
B. Misc.
C. Plant Alkaloids - ANSWER>>B
What is a normal hgb? - ANSWER>>14-18 for men
12-16 for women
Where are the most common areas of metastasis? - ANSWER>>Bone, liver, lung, brain
What is maturation/differentiation? - ANSWER>>How well the tumor cell match the
original cells
What is proliferation/division? - ANSWER>>How quickly the cells is dividing
What are the pros and cons to rapid proliferation? - ANSWER>>Pros: you can hit this
Ca. hard with the treat meant and it will respond well
Con: It can divide to fast for treatment to work
What are the pros and cons of slow proliferation? - ANSWER>>Pro: You can watch and
wait because you don't need treatment right away
Cons: Can swing to fast proliferation easily and you don't start treatment right away
,Tell me about
Grade 1 differentiation - ANSWER>>Well differentiated
Confined to organ of origin
Looks like the original cell that it comes from
70-90% survival rate
Tell me about
Grade 2 Differentiation - ANSWER>>Moderately differentiated
Local spread with close nodal involvement
45-55% survival rate
Tell me about
Grade 3 differentiation - ANSWER>>tumor fixed with extensive nodal involvement
25% survival rate
Tell me about
Grade 4 Differentiation - ANSWER>>Mets to other organs and tissues
cannot tell where the cell originated from
<5% survival rate
The Vinca Alkaloids have which dose-limiting toxicity? - ANSWER>>Neuro-toxicity
What are some examples of how you assess for neurotoxicity? - ANSWER>>Sensation
,Ability to button a shirt
Any tingling
Eye droop
Fine motor movements
Tingling
Balance
Attention span
Concentration
Etoposide (VP-16) has this known side effect with rapid transfusion -
ANSWER>>Hypotension
When administering taxanes, what is the total bilirubin requirement? - ANSWER>><1.2
Capecitabine (Xeloda) should not be taken with what medication and why? -
ANSWER>>Warfarin and coumadin
It increases the chance of have toxic levels of these drugs
What dose-limiting toxicity does Capecitabine (Xeloda) have? - ANSWER>>Palmar-
Plantar erythrodysesthesia (PPE)
When administering Fluorouracil (5FU) which toxicity is noted most in...
IVP
IV Infusion - ANSWER>>IVP-Myelosupression
, IV Infusion- GI symptoms
What foods do you avoid when taking Procarbazine?
What are some examples? - ANSWER>>Tyramine
Ex: Cheese, alcohol, cured meats, smoke fish
This metabolite drug requires vigorous hydration, dexamthasone, anti-emetics, and
folic acid? - ANSWER>>Pemetrexed (Alimta)
Where are the most common sites of metastasis? - ANSWER>>Bone, Brain, Liver, Lung
How do you treat an extravasation of an Anti-tumor antibiotic Anthracyclines? -
ANSWER>>Stop the infusion immediately and put a cold compress on the site
What is the total dose you can have of Doxorubcin? - ANSWER>><450-550mg/m^2
What is adjuvant therapy? - ANSWER>>Prophylactic treatment
Chemo after surgery
Surgery is primary treatment
What is neo-adjuvant therapy? - ANSWER>>Administer chemo prior to surgery to
shrink the tumor
What is chemotherapy? - ANSWER>>Cytotoxic drugs that destroy cancer cells or
prevent cellular replication by interfering with DNA and RNA and vital cellular proteins
