Blood Bank Clinicals Exam Practice Solution Manual Rated A+

Blood Bank Clinicals Exam Practice Solution Manual Rated A+ FY (a-b-) - Answers Most common Duffy phenotype among blacks A, H - Answers Substances present in a person with the lele HH SeSe AA genotype Ensure that AHG tests with negative results aren't false negatives - Answers Purpose of Coombs control cells Serum containing anti-H - Answers A Bombay (Oh) individuals blood specimen can be differentiated from blood specimens of normal group O persons by Le (a+ b-) - Answers Bombay individual who has inherited the Le gene will have a RBC phenotype of AHG - Answers Anti- E antibody will react best in which phase of antibody identification Fy (a-b-) - Answers Patients with which of the following red cell phenotypes are resistant to Plasmodium vivax malaria? Xg(a-) - Answers Mating of an Xg+ man with an Xg- woman would produced a son with what phenotype? Anti-I - Answers Mycoplasma pneumonia infections are associated with which blood group antibody production? Black - Answers In which population is the genetic Du usually found? Kidd - Answers Antibodies notorious for escaping detection and causing severe delayed HTR Anti-K - Answers Which antibody is associated with causing hemolytic disease of the newborn? DAT - Answers Autoimmune hemolytic anemia is detected using a? M+N- - Answers Anti M will react stronger with which phenotype? E. coli - Answers Infection with which organism is associated with naturally occurring IgM Anti-K? Uses of IAT - Answers - phenotype gets donor RBCs - major compatibility test - IgG antibody identification procedures Alloantibody has been detected - Answers What might a positive antibody screen and a negative auto control indicate? Both anti-IgG and anti-C3d - Answers Poly specific anti human globulin serum must contain? P - Answers Paroxysmal Cold Hemoglobinuria is best associated with which blood group? React best at AHG phase - Answers Which of the following is characteristic of anti-S antibodies? Lea - Answers Which of the following red cell antigens are weakly expressed or absent on red blood cells from a term neonate? Jsb is a high frequency antigen - Answers Why is it NOT easy to find compatible units for a patient with anti-Jsb? Antigens are well developed at birth - Answers Why are the M and N antigens important for paternity testing? Patient serum is tested against Group O reagent screening cells - Answers What is tested in an antibody screen? IgG - Answers Most Kidd antibodies are what immunoglobulin class? Spleen - Answers Which organ removes red blood cells coated with anti-K antibodies from circulation? absence of D - Answers In the Fisher-Race nomenclature what does "d" refer to? 18 months - Answers At what age does I antigen become detectable on infant cells? Duffy - Answers Which of the following blood group systems will often show dosage reactions? Characteristics of Duffy Antibodies - Answers -IgG - may or may not show dosage - destroyed by enzymes Eluate - Answers When performing the elution procedure, the solution containing the recovered antibody is called? Kell is a low frequency antigen - Answers Why is it relatively easy to find compatible units for a patient with anti-K? IgG - Answers What class of immunoglobulin is generally associated with hemolytic disease of the newborn? Anti-Fya - Answers Which antibody is associated with causing hemolytic disease of the newborn? An autoantibody has been detected - Answers What might a positive antibody screen and a positive auto control indicate? Xga - Answers Which of the following blood group systems is sex-linked? Cw - Answers Which of the following is identified as a variant of the Rh system? Polyspecific - Answers Which AHG reagent can test to determine if IgG, complement or both are coating red blood cells? In VIVO sensitization of RBC with antibody - Answers What is a positive DAT? Group O - Answers Reagent, screening, and panel red blood cells are always? Anti-N - Answers Antibody known to occur in patients undergoing dialysis with equipment sterilized by formaldehyde? AHG - Answers At what phase of anti human globulin test will anti-Kell best be detected? Lewis - Answers In which of the following blood group systems may the red blood cell typing change during pregnancy? Blood Warmer - Answers A patient who has a pathologic autoanti-I must be transfused with a? anti-Kpa - Answers Antibody detection cells with NOT routinely be able to detect the presence of which antibody? Jk(a+b+) - Answers Most common KIDD phenotype in white population? IgM - Answers Most Lutheran antibodies are of what class? Three reasons that Kell, Duffy, and Kidd systems are so clinically significant. - Answers 1. Cause HDN 2. Cause HTRx 3. Antigens are immunogenic Antibody screen with group O screening cells (known antigens) and patients plasma. - Answers How do we test for antibodies in the Rh system? Phenotyping using patients CS and anti-K antisera - Answers How do we test for presence or absence of the K antigen? Three reasons why Lewis antibodies do not cause hemolytic disease of the newborn? - Answers - IgM antibodies do not cross placenta - baby's cells are negative for Lewis antigens - Lea substance in secreations will neutralize the anti-Lea antibody Differences between how ABO and Duffy antibodies are formed - Answers ABO= naturally occurring