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OTC medications in Hep C patients - ANSWERcirrhosiseither acetaminophen or NSAIDs can be used in
patients without evidence of cirrhosis.
Patients with cirrhosis should AVOID NSAIDs because they increase complications of cirrhosis with
risk of bleeding and renal insufficiency as well as carry the potential for worsening ascites
management.
Patients with cirhosis APAP can be used but must be limited to <2 grams/day
Hep C and pregnancy - ANSWERRibavirin is a known teratogen and must be avoided in pregnancy.
Patients should use two forms of contraception and female patients a swell as the female partners of
male patients are recommended to avoid pregnancy while taking ribavirin as well as for 6 months
afterward due to ribavirins long half-life
Hep B exposure - ANSWERHealth care providers should receive a full series of hep B vaccinations
followed by titers 1-2 months after completing the vaccination series to ensure adequate response. If
someone has done these steps and is exposed no further action is required.
Healthcare providers with an unknown response (titer) or were unvaccinated or incompletely0
vaccinated should receive a dose of the HBIG followed by either completion of an incomplete
vaccination series or initiation of vaccines.
Healthcare providers who receive six doses of Hep B vaccine and are documented non responders
should receive two doses of HGIB separated by 1 month.
Prophylaxis should always be started based on the persons status you should not wait on the
confirmation of the source status
, vaccines - ANSWERCDC recommendations for 19-21 years of age who have not received a dose of
the meningococcal vaccine since before their 16th birthday, a catch-up booster dose should be given.
ACIP recommends a MenB series for adolescents and young adults aged 16-23 years on the basis of
shared decision making
HPV and Tdap and pregnancy - ANSWERTdap should be given during each pregnancy during weeks
27-36.
HPV catchup vaccination should be delayed until after pregnancy is completed.
Live attenuated influenza vaccine is contraindicated during pregnancy
Pneumococcal immunization recommendations - ANSWERFor those who are 65 years of age or older
the CDC recommends 1 dose of PCV15 or PCV20, which should be administered at least one year
after the most recent PPSV23.
regardless of if PCV15 or PCV20 is given, an additional dose of PPSV23 is not recommended if the
patient has already received it.
PCV13 is no longer recommended for adults nor is an additional dose of PPSV23 if one has already
been given
When should higher doses of folic acid be given during preconception care - ANSWERwomen at
higher risks of neural tube defects who could benefit from higher doses of folic acid (4-5 mg) as part
of preconception care include
-smokers
- BMI >35
- take antiepleptic drugs (CBZ or VPA)
Iron therapy during HD - ANSWERtransferrin saturation goal 30% or greater (serum iron/TIBC x 100)
serum ferritin goal >500 (correlates to iron)