D403 HLTH 3330
Understanding Substance Abuse &
Addiction
FA READINESS EXAM
Q&S
©2024/2025
,1. Which neurotransmitter is primarily associated with the
reward pathway and is often dysregulated in substance
abuse?
- A) Serotonin
- B) Dopamine
- C) Norepinephrine
- D) GABA
Correct Answer: B) Dopamine
Rationale: Dopamine is crucial for the brain's reward
system and is heavily involved in the mechanisms of
addiction.
2. What is the primary mechanism of action for opioids?
- A) Inhibition of serotonin reuptake
- B) Agonism of GABA receptors
- C) Agonism of mu-opioid receptors
- D) Stimulation of dopamine release
Correct Answer: C) Agonism of mu-opioid receptors
Rationale: Opioids primarily exert their effects through
the activation of mu-opioid receptors, leading to pain relief
and euphoria.
3. Which of the following is considered a harm reduction
strategy in substance abuse treatment?
- A) Abstinence-only programs
- B) Needle exchange programs
- C) Twelve-step programs
- D) Confrontational therapy
Correct Answer: B) Needle exchange programs
Rationale: Needle exchange programs are designed to
reduce the risk of HIV and other infections by providing
clean syringes.
©2024/2025
, ### Fill-in-the-Blank Questions
4. The __________ model of addiction suggests that
addiction is a complex interplay of biological, psychological,
and social factors.
Correct Answer: biopsychosocial
Rationale: The biopsychosocial model emphasizes the
multifaceted nature of addiction, integrating various
influences.
5. In the context of addiction, __________ refers to the
brain's adaptation to a substance, leading to decreased
sensitivity and increased consumption.
Correct Answer: tolerance
Rationale: Tolerance develops when the body adapts to
a substance, requiring more of it to achieve the same effect.
6. The __________ Theory posits that individuals seek out
drugs to avoid negative emotional states rather than to
achieve pleasure.
Correct Answer: Negative Reinforcement
Rationale: This theory highlights how individuals may use
substances to alleviate discomfort or emotional pain.
### True/False Questions
7. True or False: Substance use disorder is defined only
by the physical dependence on a substance.
Correct Answer: False
Rationale: Substance use disorder encompasses a range
of behavioral, cognitive, and physiological symptoms, not
just physical dependence.
©2024/2025
Understanding Substance Abuse &
Addiction
FA READINESS EXAM
Q&S
©2024/2025
,1. Which neurotransmitter is primarily associated with the
reward pathway and is often dysregulated in substance
abuse?
- A) Serotonin
- B) Dopamine
- C) Norepinephrine
- D) GABA
Correct Answer: B) Dopamine
Rationale: Dopamine is crucial for the brain's reward
system and is heavily involved in the mechanisms of
addiction.
2. What is the primary mechanism of action for opioids?
- A) Inhibition of serotonin reuptake
- B) Agonism of GABA receptors
- C) Agonism of mu-opioid receptors
- D) Stimulation of dopamine release
Correct Answer: C) Agonism of mu-opioid receptors
Rationale: Opioids primarily exert their effects through
the activation of mu-opioid receptors, leading to pain relief
and euphoria.
3. Which of the following is considered a harm reduction
strategy in substance abuse treatment?
- A) Abstinence-only programs
- B) Needle exchange programs
- C) Twelve-step programs
- D) Confrontational therapy
Correct Answer: B) Needle exchange programs
Rationale: Needle exchange programs are designed to
reduce the risk of HIV and other infections by providing
clean syringes.
©2024/2025
, ### Fill-in-the-Blank Questions
4. The __________ model of addiction suggests that
addiction is a complex interplay of biological, psychological,
and social factors.
Correct Answer: biopsychosocial
Rationale: The biopsychosocial model emphasizes the
multifaceted nature of addiction, integrating various
influences.
5. In the context of addiction, __________ refers to the
brain's adaptation to a substance, leading to decreased
sensitivity and increased consumption.
Correct Answer: tolerance
Rationale: Tolerance develops when the body adapts to
a substance, requiring more of it to achieve the same effect.
6. The __________ Theory posits that individuals seek out
drugs to avoid negative emotional states rather than to
achieve pleasure.
Correct Answer: Negative Reinforcement
Rationale: This theory highlights how individuals may use
substances to alleviate discomfort or emotional pain.
### True/False Questions
7. True or False: Substance use disorder is defined only
by the physical dependence on a substance.
Correct Answer: False
Rationale: Substance use disorder encompasses a range
of behavioral, cognitive, and physiological symptoms, not
just physical dependence.
©2024/2025
