, Chapter 1. Changes With Aging ? ? ? ?
Multiple Choice ?
Identify the choice that best completes the statement or answers the question.
? ? ? ? ? ? ? ? ? ? ?
1. The major impact of the physiological changes that occur with aging is:
? ?? ? ? ? ? ? ? ? ? ? ? ?
A. Reduced physiological reserve
? ? ?
B. Reduced homeostatic mechanisms
? ? ?
C. Impaired immunological response
? ? ?
D. All of the above
? ? ? ?
2. The strongest evidence regarding normal physiological aging is
? ? ? ? ? ? ?
availablethrough:
? ?
A. Randomized controlled clinical trials
? ? ? ?
B. Cross-sectional studies
? ?
C. Longitudinal studies
? ?
D. Case control studies
? ? ?
3. All of the following statements are true about laboratory values in olderadults
? ? ? ? ? ? ? ? ? ? ? ?
except:
?
A. Reference ranges are preferable
? ? ? ?
B. Abnormal findings are often due to physiological aging ? ? ? ? ? ? ?
C. Normal ranges may not be applicable for older adults ? ? ? ? ? ? ? ?
D. Reference values are not necessarilyacceptable values
? ? ? ? ? ? ?
4. Biochemical individuality is best described as: ? ? ? ? ?
A. Each individual’s variation is often much greater than that of a larger
? ? ? ? ? ? ? ? ? ? ? ?
group
B. The unique biochemical profile of a selected population
? ? ? ? ? ? ? ?
C. The truly “normal” individual—falling within average range
? ? ? ? ? ? ?
D.What the body does to the drug
? ? ? ? ? ?
, D. The side effects commonly associated with the drug
? ? ? ? ? ? ? ?
7 All the following statements are false about drug absorption except:
? ? ? ? ? ? ? ? ?
. A. Antacids increase the bioavailability of digitalis ? ? ? ? ?
B. Gastric acidity decreases with age ? ? ? ?
C. Anticholinergics increase colonic motility ? ? ?
D. Underlying chronic disease has little impact on drug absorption ? ? ? ? ? ? ? ?
8 All of the following statements are true about drug distribution in the elderlyexcept:
? ? ? ? ? ? ? ? ? ? ? ?
. A. Drugs distributed in water have lower concentration
? ? ? ? ? ?
B. Drugs distributed in fat have less intense, more prolonged effect
? ? ? ? ? ? ? ? ?
C. Drugs highly protein bound have greater potential to cause
? ? ? ? ? ? ? ?
anadverse drugreaction
? ? ?
D. The fastest way to deliver a drug to the action site is by inhalation
? ? ? ? ? ? ? ? ? ? ? ? ?
9 Men have faster and more efficient biotransformation of drugs and this is thoughtto
? ? ? ? ? ? ? ? ? ? ? ?
. ? bedue to:
? ?
A. Less obesity rates than women ? ? ? ?
B. Prostate enlargement ?
C. Testosterone
D. Less estrogen than women ? ? ?
10 The cytochrome p system involves enzymes that are generally:
? ? ? ? ? ? ? ?
. A. Inhibited by drugs ? ?
B. Induced by drugs ? ?
C. Inhibited or induced by drugs ? ? ? ?
D. Associated with decreased liver perfusion ? ? ? ?
11 A statement not shown to be true about pharmacodynamics changes with agingis:
? ? ? ? ? ? ? ? ? ? ?
. A. Decreased sensitivity to oral anticoagulants ? ? ? ?
B. Enhanced sensitivity to central nervous system drugs ? ? ? ? ? ?
C. Drug responsiveness can be influenced by patient activity level
? ? ? ? ? ? ? ?
D. There is a decreased sensitivity to beta blockers
? ? ? ? ? ? ?
12 Atypical presentation of disease in the elderly is reflected by all the followingexcept:
? ? ? ? ? ? ? ? ? ? ? ?
. A. Infection without fever ? ?
B. Depression without dysphoric mood ? ? ?
C. Myocardial infarction with chest pain and diaphoresis ? ? ? ? ? ?
D. Cardiac manifestations of thyroid disease ? ? ? ?
, 13 Functional abilities are best assessed by:
? ? ? ? ?
. A. Self-report of function
? ?
B. Observed assessment of function
? ? ?
C. A comprehensive head-to-toe examination
? ? ?
D. Family report of function
? ? ?
Multiple Choice ?
Identify the choice that best completes the statement or answers the question.
? ? ? ? ? ? ? ? ? ? ?
1. The major impact of the physiological changes that occur with aging is:
? ?? ? ? ? ? ? ? ? ? ? ? ?
A. Reduced physiological reserve
? ? ?
B. Reduced homeostatic mechanisms
? ? ?
C. Impaired immunological response
? ? ?
D. All of the above
? ? ? ?
2. The strongest evidence regarding normal physiological aging is
? ? ? ? ? ? ?
availablethrough:
? ?
A. Randomized controlled clinical trials
? ? ? ?
B. Cross-sectional studies
? ?
C. Longitudinal studies
? ?
D. Case control studies
? ? ?
3. All of the following statements are true about laboratory values in olderadults
? ? ? ? ? ? ? ? ? ? ? ?
except:
?
A. Reference ranges are preferable
? ? ? ?
B. Abnormal findings are often due to physiological aging ? ? ? ? ? ? ?
C. Normal ranges may not be applicable for older adults ? ? ? ? ? ? ? ?
D. Reference values are not necessarilyacceptable values
? ? ? ? ? ? ?
4. Biochemical individuality is best described as: ? ? ? ? ?
A. Each individual’s variation is often much greater than that of a larger
? ? ? ? ? ? ? ? ? ? ? ?
group
B. The unique biochemical profile of a selected population
? ? ? ? ? ? ? ?
C. The truly “normal” individual—falling within average range
? ? ? ? ? ? ?
D.What the body does to the drug
? ? ? ? ? ?
, D. The side effects commonly associated with the drug
? ? ? ? ? ? ? ?
7 All the following statements are false about drug absorption except:
? ? ? ? ? ? ? ? ?
. A. Antacids increase the bioavailability of digitalis ? ? ? ? ?
B. Gastric acidity decreases with age ? ? ? ?
C. Anticholinergics increase colonic motility ? ? ?
D. Underlying chronic disease has little impact on drug absorption ? ? ? ? ? ? ? ?
8 All of the following statements are true about drug distribution in the elderlyexcept:
? ? ? ? ? ? ? ? ? ? ? ?
. A. Drugs distributed in water have lower concentration
? ? ? ? ? ?
B. Drugs distributed in fat have less intense, more prolonged effect
? ? ? ? ? ? ? ? ?
C. Drugs highly protein bound have greater potential to cause
? ? ? ? ? ? ? ?
anadverse drugreaction
? ? ?
D. The fastest way to deliver a drug to the action site is by inhalation
? ? ? ? ? ? ? ? ? ? ? ? ?
9 Men have faster and more efficient biotransformation of drugs and this is thoughtto
? ? ? ? ? ? ? ? ? ? ? ?
. ? bedue to:
? ?
A. Less obesity rates than women ? ? ? ?
B. Prostate enlargement ?
C. Testosterone
D. Less estrogen than women ? ? ?
10 The cytochrome p system involves enzymes that are generally:
? ? ? ? ? ? ? ?
. A. Inhibited by drugs ? ?
B. Induced by drugs ? ?
C. Inhibited or induced by drugs ? ? ? ?
D. Associated with decreased liver perfusion ? ? ? ?
11 A statement not shown to be true about pharmacodynamics changes with agingis:
? ? ? ? ? ? ? ? ? ? ?
. A. Decreased sensitivity to oral anticoagulants ? ? ? ?
B. Enhanced sensitivity to central nervous system drugs ? ? ? ? ? ?
C. Drug responsiveness can be influenced by patient activity level
? ? ? ? ? ? ? ?
D. There is a decreased sensitivity to beta blockers
? ? ? ? ? ? ?
12 Atypical presentation of disease in the elderly is reflected by all the followingexcept:
? ? ? ? ? ? ? ? ? ? ? ?
. A. Infection without fever ? ?
B. Depression without dysphoric mood ? ? ?
C. Myocardial infarction with chest pain and diaphoresis ? ? ? ? ? ?
D. Cardiac manifestations of thyroid disease ? ? ? ?
, 13 Functional abilities are best assessed by:
? ? ? ? ?
. A. Self-report of function
? ?
B. Observed assessment of function
? ? ?
C. A comprehensive head-to-toe examination
? ? ?
D. Family report of function
? ? ?
