Which drug is likely to be prescribed for a patient with peripheral arterial disease (PAD) and
hypertension?
1) Furosemide
2) Sildenafil
3) Lorazepam
4) Ramipril - ANS 4
By which mechanism of action does simvastatin exert its effects?
1) By inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase
2) By preventing the reabsorption of bile acids
3) By activating the lipoprotein lipase enzyme
4) By inhibiting lipolysis in the adipose tissue - ANS 1
Which drug class is used in combination with cholesterol absorption inhibitors for optimum effect on
high-density lipoprotein?
1) Statins
2) Fibrates
3) Nicotinic acid
4) Bile-acid sequestrants - ANS 1
Which drug will the nurse include in a teaching session on antihyperlipidemics? Select all that apply.
One, some, or all responses may be correct.
1) Statins
2) Fibrates
3) Nicotinic acid
4) Bile-acid sequestrants
,5) Cholesterol absorption inhibitors - ANS all
Which drug is a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor?
1) Ezetimibe
2) Fenofibrate
3) Cholestyramine
4) Atorvastatin - ANS
Which underlying condition is a primary cause of peripheral arterial disease (PAD)?
1) Renal disease
2) Arteriosclerosis
3) Protein S deficiency
4) Hypertension - ANS 2
Which statement made by a patient indicates an understanding of discharge instructions on
antihyperlipidemic drugs?
1) "Antihyperlipidemic drugs will replace the other interventions I have tried to decrease my
cholesterol."
2) "It is important to double my dose if I miss one to maintain therapeutic blood levels."
3) "I will stop taking the drug if it causes nausea and vomiting."
4) "I will continue my exercise program to help increase my high-density lipoprotein serum levels -
ANS 4
Which statement by a patient about nonpharmacologic methods for cholesterol reduction indicates
the need for further learning?
1) "I should eat fish."
2) "I should avoid chicken."
3) "I should exercise daily."
, 4) "I should avoid smoking. - ANS 2
Which symptom would the nurse expect to find in a patient diagnosed with peripheral vascular
disease? Select all that apply. One, some, or all responses may be correct.
1) leg ulcers
2) pain when walking
3) weakness of the legs
4) symptoms disappearing with rest
5) numbness and coolness of the extremities - ANS all
*not muscle cramps
Which statin was the first used to decrease cholesterol after the approval and introduction of statins
into the market?
1) Niacin
2) Ezetimibe
3) Gemfibrozil
4) Lovastatin - ANS 4
Which nonpharmacologic method of cholesterol reduction would the nurse include in a teaching
session for a group of community members?
1) Hypnotherapy
2) Regular exercise
3) Increased saturated fat intake
4) Low sodium diet - ANS 2
Which statement explains the mechanism of action of ezetimibe?
1) Inhibiting absorption of dietary and biliary cholesterol in the small intestine