Manufacturing Pharmacy UPDATED
Actual Exam Questions and CORRECT
Answers
A means of administering drugs as formulated preparations is called:
a. pharmaceutical
b. drug delivery system
c. dosage forms
d. any of the above - CORRECT ANSWER- ✔✔d. any of the above
A manufacturer who produces the products of a company without manufacturing facilities is
a/ an:
a. ethical manufacturer
b. proprietary manufacturer
c. biological manufacturer
d. toll manufacturer - CORRECT ANSWER- ✔✔d. toll manufacturer
Primary package system as differentiated from secondary package systems:
a. are in direct contact with the product
b. have a direct effect on product shelf life
c. AOTA
d. None - CORRECT ANSWER- ✔✔c. AOTA
The only true tamper resistant packaging:
a. aerosol containers
b. sealed tubes
c. breakable caps
d. shrink seals - CORRECT ANSWER- ✔✔a. aerosol containers
Purified water that is free from pyrogen
,a. purified water
b. water for injection
c. Any of the choices
d. NOTA - CORRECT ANSWER- ✔✔b. water for injection
Viscosity enhancers are added to liquid preparations to:
a. improve pourability of products from container
b. improve palatability
c. both
d. none - CORRECT ANSWER- ✔✔c. both
The most inert grade of stainless steel used for high grade products
a. SS 304
b. SS 316
c. SS 3004
d. SS 3016 - CORRECT ANSWER- ✔✔b. SS 316
Filtration system which is recommended for handling large quantities is
a. gravimetric filtration
b. vacuum
c. pressure
d. cartridge filtration - CORRECT ANSWER- ✔✔c. pressure
Filling method which is advisable for highly viscous products
a. gravimetric filling
b. volumetric filling
c. any of the above
d. none - CORRECT ANSWER- ✔✔a. gravimetric filling
The advantages of emulsion over other dosage forms include:
,a. increased therapeutic effects
b. increased spreading ability
c. ability to mask unpleasant odors
d. AOTA - CORRECT ANSWER- ✔✔d. AOTA
Aggregates of powders which adhere or bond to each other to form larger particles
a. powders
b. microcapsules
c. pellets
d. granules - CORRECT ANSWER- ✔✔d. granules
Storage conditions for capsules
a. 35-50% RH
b. 21-25ºC
c. AOTA
d. NOTA - CORRECT ANSWER- ✔✔c. AOTA
Substance that "glue" powder together causing them to form granules
a. diluent
b. binder
c. lubricant
d. disintegrant - CORRECT ANSWER- ✔✔b. binder
An agent that acts between surfaces in relative motion to prevent friction and wear
a. diluent
b. binder
c. lubricant
d. disintegrant - CORRECT ANSWER- ✔✔c. lubricant
In film coating, when additives migrate to the surface, the problem is called:
, a. blistering
b. wrinkling
c. sweating
d. bloom - CORRECT ANSWER- ✔✔c. sweating
An anteroom which separates the sterile from non sterile is a/an:
a. LAF
b. airlock
c. HEPA
d. AOTA - CORRECT ANSWER- ✔✔b. airlock
Area with no more than 100 particles of 0.5 micron size per cubic foot of environment:
a. Class 0.5
b. Class 500
c. Class 100
d. Class 1000 - CORRECT ANSWER- ✔✔c. Class 100
A very simple, sensitive and fast test for pyrogens using the amoebocyte of the horse shoe
crab.
a. Pyrogen Test
b. LAL Test
c. Rabbit Test
d. Crab Test - CORRECT ANSWER- ✔✔b. LAL Test
The period in which the product remain acceptable for use:
a. Stability
b. Shelf life
c. Accelerated Stability Studies
d. any of the above - CORRECT ANSWER- ✔✔b. Shelf life
Actual Exam Questions and CORRECT
Answers
A means of administering drugs as formulated preparations is called:
a. pharmaceutical
b. drug delivery system
c. dosage forms
d. any of the above - CORRECT ANSWER- ✔✔d. any of the above
A manufacturer who produces the products of a company without manufacturing facilities is
a/ an:
a. ethical manufacturer
b. proprietary manufacturer
c. biological manufacturer
d. toll manufacturer - CORRECT ANSWER- ✔✔d. toll manufacturer
Primary package system as differentiated from secondary package systems:
a. are in direct contact with the product
b. have a direct effect on product shelf life
c. AOTA
d. None - CORRECT ANSWER- ✔✔c. AOTA
The only true tamper resistant packaging:
a. aerosol containers
b. sealed tubes
c. breakable caps
d. shrink seals - CORRECT ANSWER- ✔✔a. aerosol containers
Purified water that is free from pyrogen
,a. purified water
b. water for injection
c. Any of the choices
d. NOTA - CORRECT ANSWER- ✔✔b. water for injection
Viscosity enhancers are added to liquid preparations to:
a. improve pourability of products from container
b. improve palatability
c. both
d. none - CORRECT ANSWER- ✔✔c. both
The most inert grade of stainless steel used for high grade products
a. SS 304
b. SS 316
c. SS 3004
d. SS 3016 - CORRECT ANSWER- ✔✔b. SS 316
Filtration system which is recommended for handling large quantities is
a. gravimetric filtration
b. vacuum
c. pressure
d. cartridge filtration - CORRECT ANSWER- ✔✔c. pressure
Filling method which is advisable for highly viscous products
a. gravimetric filling
b. volumetric filling
c. any of the above
d. none - CORRECT ANSWER- ✔✔a. gravimetric filling
The advantages of emulsion over other dosage forms include:
,a. increased therapeutic effects
b. increased spreading ability
c. ability to mask unpleasant odors
d. AOTA - CORRECT ANSWER- ✔✔d. AOTA
Aggregates of powders which adhere or bond to each other to form larger particles
a. powders
b. microcapsules
c. pellets
d. granules - CORRECT ANSWER- ✔✔d. granules
Storage conditions for capsules
a. 35-50% RH
b. 21-25ºC
c. AOTA
d. NOTA - CORRECT ANSWER- ✔✔c. AOTA
Substance that "glue" powder together causing them to form granules
a. diluent
b. binder
c. lubricant
d. disintegrant - CORRECT ANSWER- ✔✔b. binder
An agent that acts between surfaces in relative motion to prevent friction and wear
a. diluent
b. binder
c. lubricant
d. disintegrant - CORRECT ANSWER- ✔✔c. lubricant
In film coating, when additives migrate to the surface, the problem is called:
, a. blistering
b. wrinkling
c. sweating
d. bloom - CORRECT ANSWER- ✔✔c. sweating
An anteroom which separates the sterile from non sterile is a/an:
a. LAF
b. airlock
c. HEPA
d. AOTA - CORRECT ANSWER- ✔✔b. airlock
Area with no more than 100 particles of 0.5 micron size per cubic foot of environment:
a. Class 0.5
b. Class 500
c. Class 100
d. Class 1000 - CORRECT ANSWER- ✔✔c. Class 100
A very simple, sensitive and fast test for pyrogens using the amoebocyte of the horse shoe
crab.
a. Pyrogen Test
b. LAL Test
c. Rabbit Test
d. Crab Test - CORRECT ANSWER- ✔✔b. LAL Test
The period in which the product remain acceptable for use:
a. Stability
b. Shelf life
c. Accelerated Stability Studies
d. any of the above - CORRECT ANSWER- ✔✔b. Shelf life
