PATHOPHYSIOLOGY - EXAM 2 - HEMATOLOGIC
DISORDERS
MC ON EXAM. 4. Renal failure would cause:
a. Hemolytic anemia
b. Post-hemorrhagic anemia
c. Anemia due to decreased production of erythrocytes - Answers -c. Anemia due to
decreased production of erythrocytes
ON EXAM Neutrophilia with a shift to the left indicated:
a. The bone marrow is unable to produce sufficient red blood cells.
b. The infection has waned and the number of circulating mature neutrophils has
returned to normal.
c. Undifferentiated lymphoblasts are proliferating in the bone marrow.
d. Demand for circulating mature neutrophils exceed supply. - Answers -d. Demand for
circulating mature neutrophils exceed supply.
M.C. question worded hemolytic anemia (same answer)
6. The morphologic classification of post-hemorrhagic anemia
is:
a. Normocytic normochromic anemia
b. Macrocytic normochromic anemia
c. Microcytic hypochromic anemia
d. Normocytic hyperchromic anemia - Answers -a. Normocytic normochromic anemia
MC ON EXAM asking which isn't a symptom of leukemia - answer was polycythemia.
Major clinical manifestations of leukemia include: - Answers -a. Fatigue due to anemia
b. Bleeding due to thrombocytopenia
c. Fever due to infection
d. Anorexia and weight loss
Compare and contrast Non-Hodgkin Lymphoma to Hodgkin Lymphoma MC ON EXAM.
- Answers -See Table 20 - PPT pg. 20
SA QUESTION asking what is a cause of secondary polycythemia. - Answers -1. Living
at high altitude
2. Chronic obstructive pulmonary disease
3. Renal carcinoma
4. Congestive heart failure
9. Which of the following would NOT be a cause of secondary polycythemia?
a. Living at high altitude
b. Chronic obstructive pulmonary disease
c. Renal carcinoma
, d. Congestive heart failure
e. Dehydration - Answers -e. Dehydration
MC ON EXAM. but different worded question about chronic condition in adult with
lymphocytes which is CLL
10. Which of the following is characterized by abrupt, rapid onset; severe bone pain;
high proliferation of immature, nonfunctional B cells (blasts) in the bone marrow and in
circulation; enlarged spleen and lymph nodes; and occurs primarily in children?
a. Acute lymphocytic leukemia (ALL)
b. Acute myelogenous leukemia (AML)
c. Chronic lymphocytic leukemia (CLL)
d. Chronic myelogenous leukemia (CML) - Answers -a. Acute lymphocytic leukemia
(ALL)
MC ON EXAM. Name 5 Normocytic, Normochromic Anemias:
1. Normal in size and hemoglobin content, but insufficient number
2. Do not share common etiologies - Answers -1. Aplastic anemia
2. Posthemorrhagic anemia
3. Hemolytic anemia MC ON EXAM.
4. Sickle cell anemia
5. Anemia of chronic inflammation
Which of the following could be associated with severe anemia?
a. Angina
b. Cardiac murmur
c. Increased levels of DPG
d. Claudication
e. All of the above - Answers -e. All of the above
7. Koilonychia and angular stomatitis are clinical manifestations of:
a. Pernicious anemia
b. Hemolytic anemia
c. Sickle cell anemia
d. Iron deficiency anemia
e. All of the above - Answers -d. Iron deficiency anemia
8. In sickle cell anemia, the erythrocytes become rigid and crescent-shaped due to
crystallization of HbS hemoglobin. Which of the following triggers crystallization and a
sickling crisis?
a. Hypoxia
b. Leukocytosis
c.Thrombocytopenia
d. Autoimmune reactions
e. All of the above - Answers -a. Hypoxia
11. A shift to the right indicates:
DISORDERS
MC ON EXAM. 4. Renal failure would cause:
a. Hemolytic anemia
b. Post-hemorrhagic anemia
c. Anemia due to decreased production of erythrocytes - Answers -c. Anemia due to
decreased production of erythrocytes
ON EXAM Neutrophilia with a shift to the left indicated:
a. The bone marrow is unable to produce sufficient red blood cells.
b. The infection has waned and the number of circulating mature neutrophils has
returned to normal.
c. Undifferentiated lymphoblasts are proliferating in the bone marrow.
d. Demand for circulating mature neutrophils exceed supply. - Answers -d. Demand for
circulating mature neutrophils exceed supply.
M.C. question worded hemolytic anemia (same answer)
6. The morphologic classification of post-hemorrhagic anemia
is:
a. Normocytic normochromic anemia
b. Macrocytic normochromic anemia
c. Microcytic hypochromic anemia
d. Normocytic hyperchromic anemia - Answers -a. Normocytic normochromic anemia
MC ON EXAM asking which isn't a symptom of leukemia - answer was polycythemia.
Major clinical manifestations of leukemia include: - Answers -a. Fatigue due to anemia
b. Bleeding due to thrombocytopenia
c. Fever due to infection
d. Anorexia and weight loss
Compare and contrast Non-Hodgkin Lymphoma to Hodgkin Lymphoma MC ON EXAM.
- Answers -See Table 20 - PPT pg. 20
SA QUESTION asking what is a cause of secondary polycythemia. - Answers -1. Living
at high altitude
2. Chronic obstructive pulmonary disease
3. Renal carcinoma
4. Congestive heart failure
9. Which of the following would NOT be a cause of secondary polycythemia?
a. Living at high altitude
b. Chronic obstructive pulmonary disease
c. Renal carcinoma
, d. Congestive heart failure
e. Dehydration - Answers -e. Dehydration
MC ON EXAM. but different worded question about chronic condition in adult with
lymphocytes which is CLL
10. Which of the following is characterized by abrupt, rapid onset; severe bone pain;
high proliferation of immature, nonfunctional B cells (blasts) in the bone marrow and in
circulation; enlarged spleen and lymph nodes; and occurs primarily in children?
a. Acute lymphocytic leukemia (ALL)
b. Acute myelogenous leukemia (AML)
c. Chronic lymphocytic leukemia (CLL)
d. Chronic myelogenous leukemia (CML) - Answers -a. Acute lymphocytic leukemia
(ALL)
MC ON EXAM. Name 5 Normocytic, Normochromic Anemias:
1. Normal in size and hemoglobin content, but insufficient number
2. Do not share common etiologies - Answers -1. Aplastic anemia
2. Posthemorrhagic anemia
3. Hemolytic anemia MC ON EXAM.
4. Sickle cell anemia
5. Anemia of chronic inflammation
Which of the following could be associated with severe anemia?
a. Angina
b. Cardiac murmur
c. Increased levels of DPG
d. Claudication
e. All of the above - Answers -e. All of the above
7. Koilonychia and angular stomatitis are clinical manifestations of:
a. Pernicious anemia
b. Hemolytic anemia
c. Sickle cell anemia
d. Iron deficiency anemia
e. All of the above - Answers -d. Iron deficiency anemia
8. In sickle cell anemia, the erythrocytes become rigid and crescent-shaped due to
crystallization of HbS hemoglobin. Which of the following triggers crystallization and a
sickling crisis?
a. Hypoxia
b. Leukocytosis
c.Thrombocytopenia
d. Autoimmune reactions
e. All of the above - Answers -a. Hypoxia
11. A shift to the right indicates:
