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PMCOL 200 – Allergies Exam Study Guide.
Allergies - answer✔caused by hyper sensitivity of the immune system to normally harmless
substances
types of allergies - answer✔hay fever
food allergies
atopic dermatitis
allergic asthma
anaphalaxis
general symptoms of allergies - answer✔red eyes
itchy rash
sneezing
runny nose
shortness of breath
swelling
how do allergies form - answer✔when the body is encountered with an unwanted antigen the
body produces immunoglobulin E antibodies
when encountered with the antigen again the antigen will bind to theses anti bodies allowing
degranulation of the mast cell releasing histamine.
histamine receptors - answer✔g protein coupled receptors
four main classes
H1 H2 H3 H4
H1 receptors - answer✔found on smooth msucles on vascular endothelial cells in the heart and
the CNS
Gq activated
activation of the H1 receptors - answer✔causes increased vascular permeability
PMCOL 200 – Allergies Exam Study Guide.
Allergies - answer✔caused by hyper sensitivity of the immune system to normally harmless
substances
types of allergies - answer✔hay fever
food allergies
atopic dermatitis
allergic asthma
anaphalaxis
general symptoms of allergies - answer✔red eyes
itchy rash
sneezing
runny nose
shortness of breath
swelling
how do allergies form - answer✔when the body is encountered with an unwanted antigen the
body produces immunoglobulin E antibodies
when encountered with the antigen again the antigen will bind to theses anti bodies allowing
degranulation of the mast cell releasing histamine.
histamine receptors - answer✔g protein coupled receptors
four main classes
H1 H2 H3 H4
H1 receptors - answer✔found on smooth msucles on vascular endothelial cells in the heart and
the CNS
Gq activated
activation of the H1 receptors - answer✔causes increased vascular permeability
