TEST BANK for Pharmacotherapeutics for Advanced Practice- A Practical Approach 5th Edition Arcangelo |ultimate guide |newest version 2024/25

,Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLE CHOICE kr




1. Nurse practitioner prescriptive authority is regulated by:
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A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing for each state
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D. The State Board of Pharmacy
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ANS: k r C PTS: k r k r 1

2. Physician Assistant (PA) prescriptive authority is regulated by:
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A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing
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D. The State Board of Medical Examiners
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ANS: k r D PTS: k r k r 1

3. Clinical judgment in prescribing includes:
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A. Factoring in the cost to the patient of the medication prescribed
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B. Always prescribing the newest medication available for the disease process
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C. Handing out drug samples to poor patients kr kr kr kr kr kr



D. Prescribing all generic medications to cut costs kr kr kr kr kr kr




ANS: k r A PTS: k r k r 1

4. Criteria for choosing an effective drug for a disorder include:
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A. Asking the patient what drug they think would work best for them
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B. Consulting nationally recognized guidelines for disease management
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C. Prescribing medications that are available as samples before writing a prescription
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D. Following U.S. Drug Enforcement Administration (DEA) guidelines for
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prescribing
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ANS: k r B PTS: k r k r 1

5. Nurse practitioner practice may thrive under health-care reform due to:
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A. The demonstrated ability of nurse practitioners to control costs and improve patient
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kr outcomes
B. The fact that nurse practitioners will be able to practice independently
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C. The fact that nurse practitioners will have full reimbursement under health-care
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reform
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D. The ability to shift accountability for Medicaid to the state level
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ANS: k r A PTS: k r k r 1

,Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
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MULTIPLE CHOICE kr




1. A patient's nutritional intake and lab work reflects hypoalbuminemia. This is critical
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to prescribing because:
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A. Distribution of drugs to target tissue may be affected kr kr kr kr kr kr kr kr



B. The solubility of the drug will not match the site of absorption
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C. There will be less free drug available to generate an effect
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D. Drugs bound to albumin are readily excreted by the kidney
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ANS: k r A PTS: k r k r 1

2. Drugs that have a significant first-pass effect:
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A. Must be given by the enteral (oral) route only
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B. Bypass the hepatic circulation kr kr kr



C. Are rapidly metabolized by the liver and may have little if any desired action
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D. Are converted by the liver to more active and fat-soluble forms
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ANS: k r C PTS: k r k r 1

3. The route of excretion of a volatile drug will likely be:
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A. The kidneys kr



B. The lungs kr



C. The bile and feces kr kr kr



D. The skin kr




ANS: k r B PTS: k r k r 1

4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of the kr kr kr kr kr kr kr kr kr kr kr kr



kr drug. Storage reservoirs:
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A. Assure that the drug will reach its intended target tissue
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B. Are the reason for giving loading doses
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C. Increase the length of time a drug is available and active kr kr kr kr kr kr kr kr kr kr



D. Are most common in collagen tissues
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ANS: k r C PTS: k r k r 1

5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
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A. Propensity to go to the target receptor kr kr kr kr kr kr



B. Biological half-life kr



C. Pharmacodynamics
D. Safety and side effects kr kr kr




ANS: k r B PTS: k r k r 1

6. Azithromycin dosing requires the first day's dose be twice those of the other 4 days of
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the prescription. This is considered a loading dose. A loading dose:
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A. Rapidly achieves drug levels in the therapeutic range kr kr kr kr kr kr kr



B. Requires four to five half-lives to attain kr kr kr kr kr kr



C. Is influenced by renal function
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, D. Is directly related to the drug circulating to the target tissues
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ANS: k r A PTS: k r k r 1

7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic
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effect is the:
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A. Minimum adverse effect level kr kr kr



B. Peak of action kr kr



C. Onset of action kr kr



D. Therapeutic range kr




ANS: k r C PTS: k r k r 1

8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
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A. When the drug has a wide therapeutic rangekr kr kr kr kr kr kr



B. When the drug will be administered for a short time only
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C. When there is a high correlation between the dose and saturation of receptor sites
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D. To determine if a drug is in the therapeutic range
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ANS: k r D PTS: k r k r 1

9. A laboratory result indicates the peak level for a drug is above the minimum toxic
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concentration. This means that the:
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A. Concentration will produce therapeutic effects kr kr kr kr



B. Concentration will produce an adverse response kr kr kr kr kr



C. Time between doses must be shortened
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D. Duration of action of the drug is too long kr kr kr kr kr kr kr kr




ANS: k r B PTS: k r k r 1

10. Drugs that are receptor agonists may demonstrate what property?
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A. Irreversible binding to the drug receptor site kr kr kr kr kr kr



B. Up-regulation with chronic use kr kr kr



C. Desensitization or down-regulation with continuous use kr kr kr kr kr



D. Inverse relationship between drug concentration and drug action
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ANS: k r C PTS: k r k r 1

11. Drugs that are receptor antagonists, such as beta blockers, may cause:
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A. Down-regulation of the drug receptor kr kr kr kr



B. An exaggerated response if abruptly discontinued
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C. Partial blockade of the effects of agonist drugs
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D. An exaggerated response to competitive drug agonists
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ANS: k r B PTS: k r k r 1

12. Factors that affect gastric drug absorption include:
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A. Liver enzyme activity kr kr



B. Protein-binding properties of the drug molecule kr kr kr kr kr



C. Lipid solubility of the drug kr kr kr kr



D. Ability to chew and swallow kr kr kr kr




ANS: k r C PTS: k r k r 1