ACLAM Written Exam Practice: 120 Mock MCQs

The answers are in bold

 Which of the following is NOT a common laboratory animal species used in research? a) Mice
b) Rats c) Dogs d) Zebrafish

 What is the primary regulatory body overseeing animal research in the United States? a) FDA
b) EPA c) USDA d) NIH

 The "3Rs" of animal research stand for: a) Replacement, Reduction, Refinement b) Reuse,
Recycle, Reduce c) Respect, Responsibility, Restraint d) None of the above

 Which of the following is an example of "Refinement" in animal research? a) Using a computer
model instead of animals b) Decreasing the number of animals used in an experiment c) Using
less invasive procedures d) All of the above

 An IACUC (Institutional Animal Care and Use Committee) is responsible for: a) Reviewing
and approving animal research protocols b) Monitoring animal care and use programs c)
Ensuring compliance with animal welfare regulations d) All of the above

 Which of the following is NOT a requirement for housing laboratory animals? a) Adequate
space b) Appropriate environmental enrichment c) Access to natural sunlight d) Clean and
comfortable bedding

 Which of the following is a common method of identifying laboratory rodents? a) Ear tags b)
Microchips c) Tattooing d) All of the above

 Which of the following is NOT a common method of euthanasia for laboratory rodents? a)
Carbon dioxide asphyxiation b) Cervical dislocation c) Decapitation d) Overdose of barbiturates

 Which of the following is a zoonotic disease that can be transmitted from non-human primates
to humans? a) Herpes B virus b) Rabies c) Tuberculosis d) All of the above

 Which of the following is the most common species of fish used in research? a) Goldfish b)
Zebrafish c) Guppies d) Betta fish

 The Guide for the Care and Use of Laboratory Animals is published by: a) USDA b) NIH c)
ILAR d) AAALAC

 Which of the following is an example of a genetically engineered mouse model? a) Knockout
mouse b) Nude mouse c) SCID mouse d) All of the above

 What is the term for the process of introducing foreign DNA into an animal's genome? a)
Cloning b) Transgenesis c) Mutagenesis d) Hybridization

 Which of the following is an example of a non-invasive imaging technique used in animal
research? a) MRI b) PET c) CT d) All of the above

,  Which of the following is a common anesthetic agent used in laboratory animals? a) Isoflurane
b) Ketamine c) Xylazine d) All of the above

 What is the term for the study of diseases in animal populations? a) Pathology b) Epidemiology
c) Microbiology d) Immunology

 Which of the following is a common method of administering drugs to laboratory animals? a)
Oral gavage b) Injection c) Inhalation d) All of the above

 What is the term for the process of breeding and raising laboratory animals in a controlled
environment? a) Husbandry b) Colony management c) Animal care d) Biosecurity

 Which of the following is a common environmental enrichment for laboratory rodents? a)
Nesting material b) Chew toys c) Hiding places d) All of the above

 Which of the following is a sign of pain or distress in laboratory animals? a) Vocalization b)
Changes in behavior c) Physiological changes d) All of the above

 Which of the following is a common method for assessing the effectiveness of analgesia in
laboratory animals? a) Grimace scales b) Von Frey filaments c) Both a and b d) Neither a nor b

 What is the term for the process of transferring an animal from one facility to another? a)
Quarantine b) Acclimatization c) Shipping d) Rehoming

 Which of the following is an important consideration when shipping laboratory animals? a)
Appropriate container size and ventilation b) Temperature and humidity control c) Access to
food and water during transport d) All of the above

 Which of the following is NOT a common biosecurity measure in laboratory animal facilities?
a) Restricted access to animal rooms b) Use of personal protective equipment c) Sharing
equipment between different animal rooms d) Regular cleaning and disinfection

 What is the term for a disease that can be transmitted from animals to humans? a) Zoonosis b)
Anthroponosis c) Epizootic d) Pandemic

 Which of the following is a common method for preventing zoonotic diseases in laboratory
animal facilities? a) Vaccination of animals b) Quarantine of new animals c) Good hygiene
practices d) All of the above

 Which of the following is an example of a sentinel animal? a) An animal used to detect
environmental contaminants b) An animal used to monitor for the presence of infectious
diseases c) An animal used to test the efficacy of vaccines d) An animal used to study the effects
of aging