TEST BANK For Karch's Focus on Nursing Pharmacology,
9th Edition by Rebecca Tucker
Uterine Motility Drugs: Abortifacients (works in the ovary) - ANSWER:drugs used to
stimulate uterine contractions and promote evacuation of the uterus to cause
abortion or to empty the uterus after fetal death. Abortifacients: carboprost,
dinoprostone, mifepristone.
Fertility Drugs - ANSWER:drugs used to stimulate ovulation and pregnancy in women
with functioning ovaries who are having trouble conceiving. Fertility Drugs:
Cetrorelix, Chorionic Gonadotropin, Chorionic Gonadotropin alpha, Clomiphene,
Follitropin Alfa, Follitropin beta, Ganirelix, Lutropin alfa, Menotropins
Urofollitropin.
Oxytocics (works in the uterus) - ANSWER:Drugs that act like the hypothalamic
hormone ocytocin; they stimulate uterine contraction to induce labor; and
contraction of the lacteal glands in the breast, promoting milk ejection.
Also indicated for the prevention and tx of uterine atony after delivery to prevent
postpartum hemorrhage
Progestins (works in the ovum) - ANSWER:The endogenous female hormone
progesterone and its various derivatives, important in maintaining a pregnancy and
supporting many secondary sex characteristics; a steroid that specifically stimulate
the uterine lining. Progestins: desogestrel, drospirenone, etonogestrel,
levonorgestrel, medroxyprogesterone, norethindrone acetate (P), norgestrel,
progesterone
estrogens (works in the ovum) - ANSWER:-steroids that stimulate female
reproductive tissue
-estradiol (P), estrogens conjugated, estrogens esterified, estropipate
Estrogen Receptor Modulators: - ANSWER:Raloxifene, Toremifene.
hormonal balance, hormone-sensitive tumors, contraception - ANSWER:Estrogen
and progestin preparations may be used to stimulate the endogenous hormones to
restore _______, treat _______, and for _______.
estrogens contraindications and cautions - ANSWER:-breast cancer, endometrial
hyperplasia, history of thromboembolism, pregnancy, lactation, heavy smokers
-caution: hypertension, gallbladder disease, liver or kidney dysfunction
progestins contraindications and cautions - ANSWER:-thromboembolic disorders,
PID, STD's, endometriosis, pelvic surgery
-caution: epilepsy, migraine headaches, asthma, cardiac or renal dysfunction
, estrogens adverse effects - ANSWER:-breakthrough bleeding, menstrual
irregularities, dysmenorrhea, amenorrhea, changes in libido
-fluid retention, electrolyte disturbances, hedache, dizziness, mental changes, weight
changes, edema
-NVD, cramps, bloating
-Potentially serious: acute pancreatitis, chelstatic jaundice, hepatic adenoma
progestins adverse effects - ANSWER:-vary w/ the administration route used
-dermal patch skin irritation
-vaginal gel: headaches, nervousness, constipation, breast enlargement, perineal
pain
-intrauterine: abdominal pain, endometriosis, abortion, PID, expulsion of device
estrogens d2d interactions - ANSWER:-barbiturates, rifampin, tetracyclines,
phenytoin (these enhance hepatic metabolism causing serum levels to decrease)
-corticosteroids: increased therapeutic and toxic effects
-smoking increases risk for thrombi and emboli
-grapefruit juice
-St. John's Wort can decrease effectiveness of contraceptives
progestins d2d interactions - ANSWER:-barbiturates, carbamazepine, phenytoin,
griseofulvin, penicillins, tetracyclines, rifampin may reduce effectiveness
-St. John's wort
estradiol (P) - ANSWER:-menopause, prostate cancer, inoperable breast cancer,
female hypogonadism, postpartum breast engorgement
estrogens conjugated - ANSWER:(CES, Premarin)
-menopause, prostate cancer, inoperable breast cancer, female hypogonadism,
postpartum breast engorgement
**retard progress of osteoporosis
estrogens esterified - ANSWER:Menest
-menopause, prostate cancer, inoperable breast cancer, female hypogonadism
estropipate - ANSWER:Ortho-Est, Ogen
-menopause, female hypogonadism
desogestrel - ANSWER:Kariva, Cyclessa
-oral contraceptive
-only in combination form
drosperinone - ANSWER:Yasmin (ethinyl estradiol), YAZ (estradiol)
-combination contraceptives w/ ethinyl estradiol, or estradiol
-acne, PMDD, menopause
etonogestrel - ANSWER:Implanon, NuvaRing (w/ ethinyl estradiol)
9th Edition by Rebecca Tucker
Uterine Motility Drugs: Abortifacients (works in the ovary) - ANSWER:drugs used to
stimulate uterine contractions and promote evacuation of the uterus to cause
abortion or to empty the uterus after fetal death. Abortifacients: carboprost,
dinoprostone, mifepristone.
Fertility Drugs - ANSWER:drugs used to stimulate ovulation and pregnancy in women
with functioning ovaries who are having trouble conceiving. Fertility Drugs:
Cetrorelix, Chorionic Gonadotropin, Chorionic Gonadotropin alpha, Clomiphene,
Follitropin Alfa, Follitropin beta, Ganirelix, Lutropin alfa, Menotropins
Urofollitropin.
Oxytocics (works in the uterus) - ANSWER:Drugs that act like the hypothalamic
hormone ocytocin; they stimulate uterine contraction to induce labor; and
contraction of the lacteal glands in the breast, promoting milk ejection.
Also indicated for the prevention and tx of uterine atony after delivery to prevent
postpartum hemorrhage
Progestins (works in the ovum) - ANSWER:The endogenous female hormone
progesterone and its various derivatives, important in maintaining a pregnancy and
supporting many secondary sex characteristics; a steroid that specifically stimulate
the uterine lining. Progestins: desogestrel, drospirenone, etonogestrel,
levonorgestrel, medroxyprogesterone, norethindrone acetate (P), norgestrel,
progesterone
estrogens (works in the ovum) - ANSWER:-steroids that stimulate female
reproductive tissue
-estradiol (P), estrogens conjugated, estrogens esterified, estropipate
Estrogen Receptor Modulators: - ANSWER:Raloxifene, Toremifene.
hormonal balance, hormone-sensitive tumors, contraception - ANSWER:Estrogen
and progestin preparations may be used to stimulate the endogenous hormones to
restore _______, treat _______, and for _______.
estrogens contraindications and cautions - ANSWER:-breast cancer, endometrial
hyperplasia, history of thromboembolism, pregnancy, lactation, heavy smokers
-caution: hypertension, gallbladder disease, liver or kidney dysfunction
progestins contraindications and cautions - ANSWER:-thromboembolic disorders,
PID, STD's, endometriosis, pelvic surgery
-caution: epilepsy, migraine headaches, asthma, cardiac or renal dysfunction
, estrogens adverse effects - ANSWER:-breakthrough bleeding, menstrual
irregularities, dysmenorrhea, amenorrhea, changes in libido
-fluid retention, electrolyte disturbances, hedache, dizziness, mental changes, weight
changes, edema
-NVD, cramps, bloating
-Potentially serious: acute pancreatitis, chelstatic jaundice, hepatic adenoma
progestins adverse effects - ANSWER:-vary w/ the administration route used
-dermal patch skin irritation
-vaginal gel: headaches, nervousness, constipation, breast enlargement, perineal
pain
-intrauterine: abdominal pain, endometriosis, abortion, PID, expulsion of device
estrogens d2d interactions - ANSWER:-barbiturates, rifampin, tetracyclines,
phenytoin (these enhance hepatic metabolism causing serum levels to decrease)
-corticosteroids: increased therapeutic and toxic effects
-smoking increases risk for thrombi and emboli
-grapefruit juice
-St. John's Wort can decrease effectiveness of contraceptives
progestins d2d interactions - ANSWER:-barbiturates, carbamazepine, phenytoin,
griseofulvin, penicillins, tetracyclines, rifampin may reduce effectiveness
-St. John's wort
estradiol (P) - ANSWER:-menopause, prostate cancer, inoperable breast cancer,
female hypogonadism, postpartum breast engorgement
estrogens conjugated - ANSWER:(CES, Premarin)
-menopause, prostate cancer, inoperable breast cancer, female hypogonadism,
postpartum breast engorgement
**retard progress of osteoporosis
estrogens esterified - ANSWER:Menest
-menopause, prostate cancer, inoperable breast cancer, female hypogonadism
estropipate - ANSWER:Ortho-Est, Ogen
-menopause, female hypogonadism
desogestrel - ANSWER:Kariva, Cyclessa
-oral contraceptive
-only in combination form
drosperinone - ANSWER:Yasmin (ethinyl estradiol), YAZ (estradiol)
-combination contraceptives w/ ethinyl estradiol, or estradiol
-acne, PMDD, menopause
etonogestrel - ANSWER:Implanon, NuvaRing (w/ ethinyl estradiol)
