TEST BANK For Huether and McCance's Understanding
Pathophysiology, Canadian 2nd Edition by Kelly Power-Kean
Anemia - ANSWER:is a reduction in the total number of erythrocytes in the
circulating blood or a decrease in the quality or quantity of hemoglobin.
Anisocytosis - ANSWER:have to do with the various sizes of erythrocytes in anemia
Poikilocytosis - ANSWER:have to do with the various shapes of erythrocytes in
anemia
cytic - ANSWER:cell size
chromic - ANSWER:have to do with hemoglobin content
Hypoxemia - ANSWER:reduced oxygen level in the blood
Hemolysis - ANSWER:accumulation of end products of red cell destruction
Dyspnea - ANSWER:shortness of breath
Jaundice - ANSWER:yellowish color of skin
Macrocytic (megaloblastic) anemias - ANSWER:are characterized by unusually large
stem cells (megaloblasts) in the marrow that mature into erythrocytes that are
unusually large in size, thickness, and volume
Eryptosis - ANSWER:Premature death of damaged erythrocytes
Pernicious anemia - ANSWER:the most common type of macrocytic anemia, is
caused by vitamin B12 deficiency
Pernicious - ANSWER:highly injurious or destructive
Intrinsic factor - ANSWER:a transporter required for gastric absorption of dietary
vitamin B12,
B12 - ANSWER:a vitamin essential for nuclear maturation and DNA synthesis in red
blood cells.
Sallow - ANSWER:skin is lemon yellow, caused by combination of pallor and jaundice
Cobalamin - ANSWER:treatment for the replacement of vitamin B12
, Folate (folic acid) - ANSWER:an essential vitamin required for RNA and DNA synthesis
within the maturing erythrocyte
Cheilosis - ANSWER:scales and fissures of the mouth
Stomatitis - ANSWER:inflammation of the mouth
Microcytic - ANSWER:hypochromic anemias- characterized by abnormally small
erythrocytes that contain abnormally reduced amounts of hemoglobin
Iron deficiency anemia - ANSWER:the most common type of anemia throughout the
world, occurring in both developing and developed countries.
Menorrhagia - ANSWER:excessive menstrual bleeding
Koilonychias - ANSWER:spoon/concave nails
Angular stomatitis - ANSWER:The corners of the mouth become dry and sore
Sideroblastic anemias - ANSWER:are a heterogeneous group of inherited and
acquired disorders characterized by anemia of varying severity and the presence of
ringed sideroblasts in the bone marrow
Ringed sideroblasts - ANSWER:are erythroblasts that contain iron-laden
mitochondria arranged in a circle around one third or more of the nucleus
Acquired sideroblastic anemias - ANSWER:the most common, occur as a primary
disorder with no known cause (idiopathic) or are associated with other
myeloproliferative or myeloplastic disorders
Reversible sideroblastic anemias - ANSWER:is secondary to various conditions such
as alcoholism, drug reactions, copper deficiency, and hypothermia.
Hereditary (congenital) sideroblastic anemias - ANSWER:are rare and occur almost
exclusively in males, supporting a recessive X-linked transmission
myelodysplastic syndrome (MDS) - ANSWER:The leading known cause of primary
ASA is a group of disorders of hematopoietic stem cells with all three stem cell lines
(erythrocytic, granulocytic, and megakaryocytic) demonstrating abnormal growth or
cell characteristics
Hypoplastic Anemia - ANSWER:deficiency of stem cells in the marrow
Phlebotomy - ANSWER:removal of blood from the circulation
Microcytosis - ANSWER:Structural abnormalities of cells
Pathophysiology, Canadian 2nd Edition by Kelly Power-Kean
Anemia - ANSWER:is a reduction in the total number of erythrocytes in the
circulating blood or a decrease in the quality or quantity of hemoglobin.
Anisocytosis - ANSWER:have to do with the various sizes of erythrocytes in anemia
Poikilocytosis - ANSWER:have to do with the various shapes of erythrocytes in
anemia
cytic - ANSWER:cell size
chromic - ANSWER:have to do with hemoglobin content
Hypoxemia - ANSWER:reduced oxygen level in the blood
Hemolysis - ANSWER:accumulation of end products of red cell destruction
Dyspnea - ANSWER:shortness of breath
Jaundice - ANSWER:yellowish color of skin
Macrocytic (megaloblastic) anemias - ANSWER:are characterized by unusually large
stem cells (megaloblasts) in the marrow that mature into erythrocytes that are
unusually large in size, thickness, and volume
Eryptosis - ANSWER:Premature death of damaged erythrocytes
Pernicious anemia - ANSWER:the most common type of macrocytic anemia, is
caused by vitamin B12 deficiency
Pernicious - ANSWER:highly injurious or destructive
Intrinsic factor - ANSWER:a transporter required for gastric absorption of dietary
vitamin B12,
B12 - ANSWER:a vitamin essential for nuclear maturation and DNA synthesis in red
blood cells.
Sallow - ANSWER:skin is lemon yellow, caused by combination of pallor and jaundice
Cobalamin - ANSWER:treatment for the replacement of vitamin B12
, Folate (folic acid) - ANSWER:an essential vitamin required for RNA and DNA synthesis
within the maturing erythrocyte
Cheilosis - ANSWER:scales and fissures of the mouth
Stomatitis - ANSWER:inflammation of the mouth
Microcytic - ANSWER:hypochromic anemias- characterized by abnormally small
erythrocytes that contain abnormally reduced amounts of hemoglobin
Iron deficiency anemia - ANSWER:the most common type of anemia throughout the
world, occurring in both developing and developed countries.
Menorrhagia - ANSWER:excessive menstrual bleeding
Koilonychias - ANSWER:spoon/concave nails
Angular stomatitis - ANSWER:The corners of the mouth become dry and sore
Sideroblastic anemias - ANSWER:are a heterogeneous group of inherited and
acquired disorders characterized by anemia of varying severity and the presence of
ringed sideroblasts in the bone marrow
Ringed sideroblasts - ANSWER:are erythroblasts that contain iron-laden
mitochondria arranged in a circle around one third or more of the nucleus
Acquired sideroblastic anemias - ANSWER:the most common, occur as a primary
disorder with no known cause (idiopathic) or are associated with other
myeloproliferative or myeloplastic disorders
Reversible sideroblastic anemias - ANSWER:is secondary to various conditions such
as alcoholism, drug reactions, copper deficiency, and hypothermia.
Hereditary (congenital) sideroblastic anemias - ANSWER:are rare and occur almost
exclusively in males, supporting a recessive X-linked transmission
myelodysplastic syndrome (MDS) - ANSWER:The leading known cause of primary
ASA is a group of disorders of hematopoietic stem cells with all three stem cell lines
(erythrocytic, granulocytic, and megakaryocytic) demonstrating abnormal growth or
cell characteristics
Hypoplastic Anemia - ANSWER:deficiency of stem cells in the marrow
Phlebotomy - ANSWER:removal of blood from the circulation
Microcytosis - ANSWER:Structural abnormalities of cells
