BBH 451 Exam 2 Practice Questions and
Correct Answers
In a chronic alcohol drinker, levels of stomach enzymes that metabolize alcohol begin to
increase, causing more alcohol to be metabolized before it reaches the bloodstream.
What kind of tolerance is this and how will it affect the amount of alcohol they need to
drink to produce the effects they desire? ✅Pharmacokinetic, they will have to drink
more alcohol to produce the effect they desire
Anhedonia generally refers to: ✅Difficulty experiencing pleasure from things in life
other than drugs
Cocaine's mechanism involves blocking the _________ of dopamine, norepinephrine,
and serotonin. ✅reuptake
Amphetamine primarily increases the intracellular concentration of dopamine by:
✅Inhibiting VMAT-2
The pharmacodynamic mechanism of methamphetamine does NOT involve:
✅increased antagonism of dopamine receptors
Which of the following is considered part of the pharmacodynamics for MDMA, but not
for amphetamine? ✅agonism of serotonin receptors
Which of the following would NOT be used as evidence that the serotonin hypothesis of
depression is incomplete? ✅When someone takes an SSRI, serotonin levels are
unchanged for about 4 weeks after administration
Most antipsychotic drugs share this mechanism as part of their pharmacodynamics:
✅Antagonism of dopamine receptors
In addition to serotonin, duloxetine inhibits the reuptake of what other neurotransmitter?
✅norepinephrine
True or False: Schizophrenia is another term for multiple personality disorder. ✅False
The primary mechanism of action of the amphetamines involves: ✅causing increased
release of dopamine, norepinephrine, and serotonin
Patients who take this type of drug must be vigilant about their diet to make sure they
don't consume foods high in tyramine: ✅MAO-I
Correct Answers
In a chronic alcohol drinker, levels of stomach enzymes that metabolize alcohol begin to
increase, causing more alcohol to be metabolized before it reaches the bloodstream.
What kind of tolerance is this and how will it affect the amount of alcohol they need to
drink to produce the effects they desire? ✅Pharmacokinetic, they will have to drink
more alcohol to produce the effect they desire
Anhedonia generally refers to: ✅Difficulty experiencing pleasure from things in life
other than drugs
Cocaine's mechanism involves blocking the _________ of dopamine, norepinephrine,
and serotonin. ✅reuptake
Amphetamine primarily increases the intracellular concentration of dopamine by:
✅Inhibiting VMAT-2
The pharmacodynamic mechanism of methamphetamine does NOT involve:
✅increased antagonism of dopamine receptors
Which of the following is considered part of the pharmacodynamics for MDMA, but not
for amphetamine? ✅agonism of serotonin receptors
Which of the following would NOT be used as evidence that the serotonin hypothesis of
depression is incomplete? ✅When someone takes an SSRI, serotonin levels are
unchanged for about 4 weeks after administration
Most antipsychotic drugs share this mechanism as part of their pharmacodynamics:
✅Antagonism of dopamine receptors
In addition to serotonin, duloxetine inhibits the reuptake of what other neurotransmitter?
✅norepinephrine
True or False: Schizophrenia is another term for multiple personality disorder. ✅False
The primary mechanism of action of the amphetamines involves: ✅causing increased
release of dopamine, norepinephrine, and serotonin
Patients who take this type of drug must be vigilant about their diet to make sure they
don't consume foods high in tyramine: ✅MAO-I
