MCB4203 150 Exam Questions And
Accurate Answers
If one cannot purify a microbial agent that causes disease because the bacterium
cannot be cultured, would Koch's postulated be satisfied?
a) no, the bacterium or virus has to be purified and cultured to demonstrate that a given
microbe is an agent of a disease
b) no, because the Koch's postulates only apply to a viral infection
c) yes, Koch's postulates do not apply to non-culturable organisms
d) yes, Koch's postulates simply state that one can re-infect animal, so the healthy and
diseases animals can be instead kept together for easy transmission of an agent. -
Answer no, the bacterium or virus has to be purified and cultured to demonstrate that a
given microbe is an agent of a disease
What is a causative agent of the bubonic plague?
a) salmonella typhimurium
b) klebsiella pneumoniae
c) iraquibacter
d) yersinia pestis - Answer yersinia pestis
What was the accomplishment of Antonie van Leewenhoeck?
a) drafted the germ theory postulates
b) improved the fermentation methods
c) designed the first microscopes
d) discovered penicillin - Answer designed the first microscopes
Penicillin was first used in 1943. When were the Penicillin-resistance bacteria
identified?
a) 2011
b) 1670
c) 1940
d) 2019 - Answer 1940
,Escherichia coli O157:H7 is a bacterium that causes foodborne infections. What do O
and H signify in the nomenclature of this bacterium?
a) O and H are abbreviations of proteins that bind E. coli
b) O is LPS antigen, and H is flagella antigen
c) O and H stand for the resistance to antibiotics, oritavancin and hyrgromycin
d) OH are the initials of the person who first discovered this bacterium - Answer O is LPS
antigen, and H is flagella antigen
T/F The longer human co-evolved with pathogens, the more likely that bacterium causes
a particular disease. - Answer False
Best way to decrease the incidence of anti-microbial resistance
a) prescribe antibiotics only when absolutely needed
b) add antibiotics to water supply
c) prescribe more antibiotics
d) limit the use of antibiotics to farms and animals and stop using them in humans -
Answer prescribe antibiotics only when absolutely needed
what is an extra layer in the cell envelope that Gram-negative have in comparison to
Gram-positive bacteria?
a) inner membrane
b) mycolic acid membrane
c) outer membrane
d) Gram-negative bacteria have no membrane - Answer outer membrane
What are PAMPs
a) component of bacteria that are recognized by such receptors like Toll-like receptors
b) antibody that coats a pathogen
c) a type of vasodilating cytokine
d) type of ATPases found on a phagosome that reduce the pH - Answer -component of
bacteria that are recognized by such host receptors like Toll-like receptors - pathogen
associated molecular patterns
Select three features which describe the endothelial cell
a) lines the blood vessels inside the vessel
, b) layer of cells only inside the body
c) difficult to breach
d) a layer of cells exposed to the environment
e) present on skin
f) easy to breach - Answer -lines the blood vessels inside the vessel -layer of cells only
inside the body -easy to breach
What is the function of C3 convertase?
a) it is a protease that activates C3 into C3a and C3b
b) it is a cytokine that coats bacteria
c) it binds mannose on the surface of some bacteria
d) it binds antibody on the surface of bacteria - Answer it is a protease that activates C3
into C3a and C3b
ciliated epithelium - Answer respiratory tract
stratified squamous epithelium - Answer skin on a hand
simple columnar epithelium - Answer small intestine
simple squamous epithelium - Answer heart
how many epithelia layers does the skin have? - Answer many
does the skin have a neutral or low pH? - Answer low pH
Does the skin provide a dry or humid environment? - Answer dry
How many layers does the mucosal tissue have? - Answer only one epithelial layer
Does the mucosal tissue have a low or neutral pH? - Answer neutral
Does the mucosal layer provide a dry or humid environment? - Answer humid
How is the myeloperoxidase actively regulated
a) it is activated when in contact with a NADPH oxidase
b) it is activated by LPS
c) it is activated upon low pH
d) it is activated upon high pH
e) it is down-regulated by defensins - Answer -it is activated when in contact with a
Accurate Answers
If one cannot purify a microbial agent that causes disease because the bacterium
cannot be cultured, would Koch's postulated be satisfied?
a) no, the bacterium or virus has to be purified and cultured to demonstrate that a given
microbe is an agent of a disease
b) no, because the Koch's postulates only apply to a viral infection
c) yes, Koch's postulates do not apply to non-culturable organisms
d) yes, Koch's postulates simply state that one can re-infect animal, so the healthy and
diseases animals can be instead kept together for easy transmission of an agent. -
Answer no, the bacterium or virus has to be purified and cultured to demonstrate that a
given microbe is an agent of a disease
What is a causative agent of the bubonic plague?
a) salmonella typhimurium
b) klebsiella pneumoniae
c) iraquibacter
d) yersinia pestis - Answer yersinia pestis
What was the accomplishment of Antonie van Leewenhoeck?
a) drafted the germ theory postulates
b) improved the fermentation methods
c) designed the first microscopes
d) discovered penicillin - Answer designed the first microscopes
Penicillin was first used in 1943. When were the Penicillin-resistance bacteria
identified?
a) 2011
b) 1670
c) 1940
d) 2019 - Answer 1940
,Escherichia coli O157:H7 is a bacterium that causes foodborne infections. What do O
and H signify in the nomenclature of this bacterium?
a) O and H are abbreviations of proteins that bind E. coli
b) O is LPS antigen, and H is flagella antigen
c) O and H stand for the resistance to antibiotics, oritavancin and hyrgromycin
d) OH are the initials of the person who first discovered this bacterium - Answer O is LPS
antigen, and H is flagella antigen
T/F The longer human co-evolved with pathogens, the more likely that bacterium causes
a particular disease. - Answer False
Best way to decrease the incidence of anti-microbial resistance
a) prescribe antibiotics only when absolutely needed
b) add antibiotics to water supply
c) prescribe more antibiotics
d) limit the use of antibiotics to farms and animals and stop using them in humans -
Answer prescribe antibiotics only when absolutely needed
what is an extra layer in the cell envelope that Gram-negative have in comparison to
Gram-positive bacteria?
a) inner membrane
b) mycolic acid membrane
c) outer membrane
d) Gram-negative bacteria have no membrane - Answer outer membrane
What are PAMPs
a) component of bacteria that are recognized by such receptors like Toll-like receptors
b) antibody that coats a pathogen
c) a type of vasodilating cytokine
d) type of ATPases found on a phagosome that reduce the pH - Answer -component of
bacteria that are recognized by such host receptors like Toll-like receptors - pathogen
associated molecular patterns
Select three features which describe the endothelial cell
a) lines the blood vessels inside the vessel
, b) layer of cells only inside the body
c) difficult to breach
d) a layer of cells exposed to the environment
e) present on skin
f) easy to breach - Answer -lines the blood vessels inside the vessel -layer of cells only
inside the body -easy to breach
What is the function of C3 convertase?
a) it is a protease that activates C3 into C3a and C3b
b) it is a cytokine that coats bacteria
c) it binds mannose on the surface of some bacteria
d) it binds antibody on the surface of bacteria - Answer it is a protease that activates C3
into C3a and C3b
ciliated epithelium - Answer respiratory tract
stratified squamous epithelium - Answer skin on a hand
simple columnar epithelium - Answer small intestine
simple squamous epithelium - Answer heart
how many epithelia layers does the skin have? - Answer many
does the skin have a neutral or low pH? - Answer low pH
Does the skin provide a dry or humid environment? - Answer dry
How many layers does the mucosal tissue have? - Answer only one epithelial layer
Does the mucosal tissue have a low or neutral pH? - Answer neutral
Does the mucosal layer provide a dry or humid environment? - Answer humid
How is the myeloperoxidase actively regulated
a) it is activated when in contact with a NADPH oxidase
b) it is activated by LPS
c) it is activated upon low pH
d) it is activated upon high pH
e) it is down-regulated by defensins - Answer -it is activated when in contact with a
