PHARMACOLOGY NURSING EXAM
(ACTUAL EXAM) WITH CORRECT 250+
ACTUAL QUESTIONS AND CORRECTLY
WELL DEFINED ANSWERS LATEST 2024
ALREADY GRADED A+
Progestins (mechanism, use) - ANSWERS--Mechanism: bind
progesterone receptors, decrease growth and increase vascularization
of the endometrium
-Used in oral contraceptives and to treat endometrial cancer, abnormal
uterine bleeding.
Mifepristone (RU-486) (mechanism, use, toxicity) - ANSWERS--
Mechanism: competitive inhibitor of progestins at progesterone
receptors.
-Use: termination of pregnancy. Administered with misoprostol (PGE1).
Toxicity: heavy bleeding, GI effects (nausea, vomiting, anorexia),
abdominal pain.
,What are the major functions of the β1 receptor? - ANSWERS-Increase
heart rate, increase contractility, increase renin release, increase
lipolysis
What are the major functions of the β2 receptor? - ANSWERS-
Vasodilation, bronchodilation, increase lipolysis, increase insulin
release, decrease uterine tone (tocolysis), ciliary muscle relaxation,
increase aqueous humor production
What are the major functions of the M1 receptor? - ANSWERS-CNS,
enteric nervous system
What are the major functions of the M2 receptor? - ANSWERS-
Decrease heart rate and contractility of atria
What are the major functions of the M3 receptor? - ANSWERS-Increase
exocrine gland secretions (e.g., lacrimal, salivary, gastric acid), increase
gut peristalsis, increase bladder contraction, increase
bronchoconstriction, pupillary sphincter muscle contraction (miosis),
ciliary muscle contraction (accommodation)
What are the major functions of the α1 receptor? - ANSWERS-Increase
vascular smooth muscle contraction, increase pupillary dilator muscle
,contraction (mydriasis), increase intestinal and bladder sphincter
muscle contraction
What are the major functions of the α2 receptor? - ANSWERS-Decrease
sympathetic outflow, decrease insulin release, decrease lipolysis,
increase platelet aggregation, decrease aqueous humor production
What are the major functions of the D1 receptor? - ANSWERS-Relaxes
renal vascular smooth muscle
What are the major functions of the D2 receptor? - ANSWERS-
Modulates transmitter release, especially in the brain
What are the major functions of the H1 receptor? - ANSWERS-Increase
nasal and bronchial mucus production, increase vascular permeability,
contraction of bronchioles, pruritis, pain
What are the major functions of the H2 receptor? - ANSWERS-Increase
gastric acid secretion
What are the major functions of the V1 receptor? - ANSWERS-Increase
vascular smooth muscle contraction
, What are the major functions of the V2 receptor? - ANSWERS-Increase
H2O permeability and reabsorption in collecting tubules of kidney (V2 is
found in the "2" kidneys)
What receptors are associate with Gq? - ANSWERS-H1, α1, V1, M1, and
M3
What receptors are associated with Gs? - ANSWERS-H2, B1, B2, V2, D1
What receptors are associated with Gi? - ANSWERS-M2, α2, D2
Bethanechol - ANSWERS--Direct cholinergic agonist
-Activates bowel and bladder smooth muscle
-Used in postoperative and neurogenic ileus
-Resistant to AChE
Carbachol - ANSWERS--Direct cholinergic agonist
-Carbon copy of acetylcholine
-Constricts pupils and relieves intraocular pressure in glaucoma
Methacholine - ANSWERS--Direct cholinergic agonist
(ACTUAL EXAM) WITH CORRECT 250+
ACTUAL QUESTIONS AND CORRECTLY
WELL DEFINED ANSWERS LATEST 2024
ALREADY GRADED A+
Progestins (mechanism, use) - ANSWERS--Mechanism: bind
progesterone receptors, decrease growth and increase vascularization
of the endometrium
-Used in oral contraceptives and to treat endometrial cancer, abnormal
uterine bleeding.
Mifepristone (RU-486) (mechanism, use, toxicity) - ANSWERS--
Mechanism: competitive inhibitor of progestins at progesterone
receptors.
-Use: termination of pregnancy. Administered with misoprostol (PGE1).
Toxicity: heavy bleeding, GI effects (nausea, vomiting, anorexia),
abdominal pain.
,What are the major functions of the β1 receptor? - ANSWERS-Increase
heart rate, increase contractility, increase renin release, increase
lipolysis
What are the major functions of the β2 receptor? - ANSWERS-
Vasodilation, bronchodilation, increase lipolysis, increase insulin
release, decrease uterine tone (tocolysis), ciliary muscle relaxation,
increase aqueous humor production
What are the major functions of the M1 receptor? - ANSWERS-CNS,
enteric nervous system
What are the major functions of the M2 receptor? - ANSWERS-
Decrease heart rate and contractility of atria
What are the major functions of the M3 receptor? - ANSWERS-Increase
exocrine gland secretions (e.g., lacrimal, salivary, gastric acid), increase
gut peristalsis, increase bladder contraction, increase
bronchoconstriction, pupillary sphincter muscle contraction (miosis),
ciliary muscle contraction (accommodation)
What are the major functions of the α1 receptor? - ANSWERS-Increase
vascular smooth muscle contraction, increase pupillary dilator muscle
,contraction (mydriasis), increase intestinal and bladder sphincter
muscle contraction
What are the major functions of the α2 receptor? - ANSWERS-Decrease
sympathetic outflow, decrease insulin release, decrease lipolysis,
increase platelet aggregation, decrease aqueous humor production
What are the major functions of the D1 receptor? - ANSWERS-Relaxes
renal vascular smooth muscle
What are the major functions of the D2 receptor? - ANSWERS-
Modulates transmitter release, especially in the brain
What are the major functions of the H1 receptor? - ANSWERS-Increase
nasal and bronchial mucus production, increase vascular permeability,
contraction of bronchioles, pruritis, pain
What are the major functions of the H2 receptor? - ANSWERS-Increase
gastric acid secretion
What are the major functions of the V1 receptor? - ANSWERS-Increase
vascular smooth muscle contraction
, What are the major functions of the V2 receptor? - ANSWERS-Increase
H2O permeability and reabsorption in collecting tubules of kidney (V2 is
found in the "2" kidneys)
What receptors are associate with Gq? - ANSWERS-H1, α1, V1, M1, and
M3
What receptors are associated with Gs? - ANSWERS-H2, B1, B2, V2, D1
What receptors are associated with Gi? - ANSWERS-M2, α2, D2
Bethanechol - ANSWERS--Direct cholinergic agonist
-Activates bowel and bladder smooth muscle
-Used in postoperative and neurogenic ileus
-Resistant to AChE
Carbachol - ANSWERS--Direct cholinergic agonist
-Carbon copy of acetylcholine
-Constricts pupils and relieves intraocular pressure in glaucoma
Methacholine - ANSWERS--Direct cholinergic agonist
