Physiology MCQ
General physiology
1) Cell membrane
a. formed entirely of protein molecules b. are impermeable to fat soluble substances
c. in some tissues permit permit transport of
glucose at a greater rate in the presence of d. are not changed through out the life
insulin
Ans. c
2) The substance that contributes maximally to the osmolality inside the cell is
a. protein b. phosphate
c. urea d. potassium
Ans. c
3) Proteins that are secreted by cells are generally
a. not synthesized on ribosomes that are
b. are synthesized in the mitochondria
bound to endoplasmic reticulum
d. moves across the cell membrane by
c. packed in the golgi apparatus
endocytosis
Ans. c
4) The unique feature in mitochondria is
a. myosin b. actin
c. DNA d. prothrombin
Ans. c
5) The resting membrane potential of a cell
a. is dependant on the permeability of the b. falls to zero if Na+/K+ ATPase in
cell membrane to K+ being greater to Na+ membrane is inhibited
c. is equal to the equilibrium potential for d. is equal to the equilibrium potential of
K+ Na+
Ans. a
6) The somatic cells containing the full complement of 46 chromosomes in their
nuclei, containing all the genes necessary for carrying out the cell activities are
called
a. autosomes b. haploid cells
c. allosomes d. diploid cells
Ans. d
7) In some cases DM is due to
a. excessive receptors b. antibodies against receptors
c. deficiency of receptors for extra cellular d. deficiency of nucleotide regulatory G
proteins proteins
,Ans. b
8) Many substances are removed from the cell to outside by
a. pinocytosis b. chemotaxis
c. phagocytosis c. exocytosis
Ans. d
9) Excessive formation of a substance/ secretion in the body is controlled in order to
maintain homeostasis by
a. +ve feedback mechanism b. -ve feedback mechanism
c. osmosis d. haemodynamics
Ans. b
10 ) An action potential in a nerve
a. is terminated by influx of Na+ excessive
b. is terminated by efflux of K+
receptors
c. is initiated by efflux of Na+ d. is initiated by influx of K+
Ans. b
11)" Milieu interior " is a term introduced by
a. Laplace b. Boyle
c. Claud Bernard d. Lansteiner
Ans. c
12) An example of co-transport is
a. Na+-K+ pump b. Ca++ pump
c. Na+- H+ pump d. Na+ glucose transport
Ans.d
Nerve Muscle
1) Which of the following has slowest conduction
a. A alpha b. A gamma
c. B fibres d. C fibres
Ans. d
2) A man falls into deep sleep with one arm under his head. After awakening the
arm is paralyzed but tingling sensation and pain sensation persists. This loss of
motor function without the loss of sensory function is due to
a. A fibres are more susceptible to hypoxia b. A fibres are more sensitive to pressure
that B than C
c. C fibres are more sensitive to pressure d. Sensory nerves are nearer bone and hence
than A affected by pressure
Ans. b
3) Saltatory conduction
a. is seen only in myelinated nerve fibres b. is slower that non saltatory conduction
, c. is not affected if a local anesthetic is
d. none of the above
applied to the node of Ranvier
Ans. a
4) Myelin sheath is produced by
a. axoplasm b. mitochondria
c. scawann cell d. muscle cell
Ans. c
5) The action potential of skeletal muscle
b. spreads inwards to all parts of the muscle
a. has a prolonged plateau phase
via T tubules
c. is longer than the action potential of
d. is not essential for muscle conduction
cardiac muscle
Ans. b
6) Smooth muscle need help of
a. calmodulin for contraction b. acetyl choline for contraction
c.K+ for contraction d. monoamine oxidase for contraction
Ans. a
7) The cross bridges of the sarcomere in skeletal muscle are components of
a. actin b. myosin
c. troponin d. tropomyosin
Ans. b
8) The likely mechanism through which neostigmine acts in improving muscular
weakness is
b. it interferes with action of mono-amine
a. It blocks action of acetylcholine
oxidase
d. it blocks the action of acetyl choline
c. it enhances the action of catecholamines
esterase
Ans. d
9) A skeletal muscle
b. becomes less excitable when its
a. obeys all or none phenomenon
membrane becomes hyperpolarized
c. has a resting membrane potential positive d. contains excessive Na+ in intracellular
inside compartment
Ans. a
10) The function of tropomyosin in skeletal muscle is-
b. Releasing Ca++ after initiation of
a. sliding on actin to produce shortening
contraction
d. covering up the actin binding sites of
c. binding to myosin during contraction
myosin at rest
General physiology
1) Cell membrane
a. formed entirely of protein molecules b. are impermeable to fat soluble substances
c. in some tissues permit permit transport of
glucose at a greater rate in the presence of d. are not changed through out the life
insulin
Ans. c
2) The substance that contributes maximally to the osmolality inside the cell is
a. protein b. phosphate
c. urea d. potassium
Ans. c
3) Proteins that are secreted by cells are generally
a. not synthesized on ribosomes that are
b. are synthesized in the mitochondria
bound to endoplasmic reticulum
d. moves across the cell membrane by
c. packed in the golgi apparatus
endocytosis
Ans. c
4) The unique feature in mitochondria is
a. myosin b. actin
c. DNA d. prothrombin
Ans. c
5) The resting membrane potential of a cell
a. is dependant on the permeability of the b. falls to zero if Na+/K+ ATPase in
cell membrane to K+ being greater to Na+ membrane is inhibited
c. is equal to the equilibrium potential for d. is equal to the equilibrium potential of
K+ Na+
Ans. a
6) The somatic cells containing the full complement of 46 chromosomes in their
nuclei, containing all the genes necessary for carrying out the cell activities are
called
a. autosomes b. haploid cells
c. allosomes d. diploid cells
Ans. d
7) In some cases DM is due to
a. excessive receptors b. antibodies against receptors
c. deficiency of receptors for extra cellular d. deficiency of nucleotide regulatory G
proteins proteins
,Ans. b
8) Many substances are removed from the cell to outside by
a. pinocytosis b. chemotaxis
c. phagocytosis c. exocytosis
Ans. d
9) Excessive formation of a substance/ secretion in the body is controlled in order to
maintain homeostasis by
a. +ve feedback mechanism b. -ve feedback mechanism
c. osmosis d. haemodynamics
Ans. b
10 ) An action potential in a nerve
a. is terminated by influx of Na+ excessive
b. is terminated by efflux of K+
receptors
c. is initiated by efflux of Na+ d. is initiated by influx of K+
Ans. b
11)" Milieu interior " is a term introduced by
a. Laplace b. Boyle
c. Claud Bernard d. Lansteiner
Ans. c
12) An example of co-transport is
a. Na+-K+ pump b. Ca++ pump
c. Na+- H+ pump d. Na+ glucose transport
Ans.d
Nerve Muscle
1) Which of the following has slowest conduction
a. A alpha b. A gamma
c. B fibres d. C fibres
Ans. d
2) A man falls into deep sleep with one arm under his head. After awakening the
arm is paralyzed but tingling sensation and pain sensation persists. This loss of
motor function without the loss of sensory function is due to
a. A fibres are more susceptible to hypoxia b. A fibres are more sensitive to pressure
that B than C
c. C fibres are more sensitive to pressure d. Sensory nerves are nearer bone and hence
than A affected by pressure
Ans. b
3) Saltatory conduction
a. is seen only in myelinated nerve fibres b. is slower that non saltatory conduction
, c. is not affected if a local anesthetic is
d. none of the above
applied to the node of Ranvier
Ans. a
4) Myelin sheath is produced by
a. axoplasm b. mitochondria
c. scawann cell d. muscle cell
Ans. c
5) The action potential of skeletal muscle
b. spreads inwards to all parts of the muscle
a. has a prolonged plateau phase
via T tubules
c. is longer than the action potential of
d. is not essential for muscle conduction
cardiac muscle
Ans. b
6) Smooth muscle need help of
a. calmodulin for contraction b. acetyl choline for contraction
c.K+ for contraction d. monoamine oxidase for contraction
Ans. a
7) The cross bridges of the sarcomere in skeletal muscle are components of
a. actin b. myosin
c. troponin d. tropomyosin
Ans. b
8) The likely mechanism through which neostigmine acts in improving muscular
weakness is
b. it interferes with action of mono-amine
a. It blocks action of acetylcholine
oxidase
d. it blocks the action of acetyl choline
c. it enhances the action of catecholamines
esterase
Ans. d
9) A skeletal muscle
b. becomes less excitable when its
a. obeys all or none phenomenon
membrane becomes hyperpolarized
c. has a resting membrane potential positive d. contains excessive Na+ in intracellular
inside compartment
Ans. a
10) The function of tropomyosin in skeletal muscle is-
b. Releasing Ca++ after initiation of
a. sliding on actin to produce shortening
contraction
d. covering up the actin binding sites of
c. binding to myosin during contraction
myosin at rest
