ASCP BOC Hematology
Questions and Answers
____________ and ____________ are required for heme synthesis
✓~ iron and protoporphyrin
Fe Transport protein
✓~ Transferrin
Major Fe storage form
✓~ Ferritin
H2O insoluble Fe storage form (long-term)
✓~ Hemosiderin
Excess iron that is stored in tissues and body organs can lead to ____________ and
____________
✓~ hemosiderosis and hemochromatosis (organ damage)
What are the heme precursors (in order)
, ✓~ Delta, Porphobilinogen, UR, COP, PROTO
EDTA chelates ____
✓~ Calcium
What are some sources of error for hemoglobin?
✓~ icterus, lipemia, hemolysis, increased white count
What are the hemoglobin reference ranges for men and women?
✓~ men: 16 +- 2 g/dL
women: 14 +- 2 g/dL
What happens in methemoglobin?
✓~ Fe2+ is oxidized to Fe3+, cannot bind O2, is brown
Measures packed cell volume in a percent
✓~ hematocrit
What are some sources of error from a calculated hematocrit?
✓~ cold agglutinins, high white count
Questions and Answers
____________ and ____________ are required for heme synthesis
✓~ iron and protoporphyrin
Fe Transport protein
✓~ Transferrin
Major Fe storage form
✓~ Ferritin
H2O insoluble Fe storage form (long-term)
✓~ Hemosiderin
Excess iron that is stored in tissues and body organs can lead to ____________ and
____________
✓~ hemosiderosis and hemochromatosis (organ damage)
What are the heme precursors (in order)
, ✓~ Delta, Porphobilinogen, UR, COP, PROTO
EDTA chelates ____
✓~ Calcium
What are some sources of error for hemoglobin?
✓~ icterus, lipemia, hemolysis, increased white count
What are the hemoglobin reference ranges for men and women?
✓~ men: 16 +- 2 g/dL
women: 14 +- 2 g/dL
What happens in methemoglobin?
✓~ Fe2+ is oxidized to Fe3+, cannot bind O2, is brown
Measures packed cell volume in a percent
✓~ hematocrit
What are some sources of error from a calculated hematocrit?
✓~ cold agglutinins, high white count
