NURS 615 maryville exam 2 Questions and Verified Correct Answers | Grade A+

Drugs with CNS effects act of what receptors (neurotransmitters) Ans: GABA Acetylcholine Seratonin Dopamine Norepinephrine Anti- anxiety drugs, and sedative hypnotic drug classes Ans: Benzodiazapimes, atypical anxiolytics, sedative hypnotics, barbituates Benzodiazepine drugs Ans: All the "pams" plus librium Alprazolam (Xanax) Chlordiazepoxide (Librium) Clonazepam (Klonopin) Diazepam (Valium) Lorazepam (Ativan) Oxazepam (Serax) Benzodiazepine like drugs Ans: Eszopiclone (Lunesta) Zolpidem (Ambien) Mechanism of action of benzodiazepine Ans: increases the action of GABA (an inhibitory neurotransmitter) thereby decreasing neuronal excitation. Benzos bind to the benzodiazepine receptor. When GABA increases, it decreases neuronal excitation=reduction in anxiety, muscle relaxation, and anticonvulsant. Metabolized in the liver- highly lipid soluble & protein bound Adverse effects of benzodiazepines Ans: Major effects due to action as CNS depressant- sedation, cardiac and resp depressant, depression, confusion, hypotention May also see paradoxical anxiety, agitation, and acute rage Psychological and physical dependence Considerations with benzodiazepines Ans: Development of dependence- must taper off as it can cause physical and psychological withdrawal symptom