NR 565 Midterm Study Guide
ACE inhibitors contraindications - correct answer-African American, 2nd/3rd timester
pregnancy, renal disease
ACEI and ARBs can lead to renal failure in who? - correct answer-Patients w/ bilateral renal
artery stenosis
Alternative treatment strategies for statin intolerant patients - correct answer-ezetimibe,
fibrates, nicotinic acid, bile acid sequestrates
combo therapy with infrequent statin dosing
dietary changes
switching to a different statin
appropriate intervals for medication adjustments - correct answer-4-6 weeks is ideal before
adding another drug to the therapy regimen
Beer's Criteria - correct answer-Criteria for "Potentially Inappropriate Medication Use in
Older Adults"; identifies drugs with a high likelihood of causing adverse effects in older adults
pg. 62 in textbook for table
Beta Blockers Contraindications - correct answer-severe HF, Bradycardia, Advanced Heart
block, Hypotension (persistent), cardiogenic shock
BP meds approved for pregnancy - correct answer-Labetalol and Methyldopa
Carbamazepine drug interactions & dosing considerations - correct answer-narrow
therapeutic dose (toxicity is a risk)
CCB Mech of action - correct answer-Promotes relaxation of peripheral arterioles resulting in
a decreased afterload which reduces cardiac oxygen demand
classes of controlled substances: - correct answer-Anabolic steroids, narcotics, stimulants,
depressants, and hallucinogens
clinical tools for treating hyperlipidemia - correct answer-ASCVD risk category, AHA/ACC,
clinical guidelines
CYP450 inducers and inhibitors - correct answer-inducers:
carbamazepine
phenobarbital
phenytoin
, rifampin
griseofulvin
inhibitors:
cimetidine
ciprofloxacin
erythromycin
all azole antifungals
grapefruit juice
isoniazid
ritonavir protease inhibitors
DEA (Federal Drug Enforcement Administration) - correct answer-regulate drugs and other
substances based on their potential for abuse and dependence
digoxin dosaging adjustments and cautions - correct answer-start low, risk of toxicity,
requires frequent monitoring of serum levels;
do not use w/ quinidine
drug of choice for lowering LDL - correct answer-Statins
drug schedules - schedule 2 - correct answer-combination drugs w/ < 15mg hydrocodone
per dosage unit
High potential for abuse and severe physical/psychological dependence
examples:
Vicodin, cocaine, methamphetamine, methadone, Dilaudid, oxycodone, Meperidine,
Fentanyl, Adderall, Ritalin
drug schedules - schedule 3 - correct answer-drugs w/ <90 mg of codeine per dosage unit
abuse would lead to mod-low physical dependence and high psychological dependence
examples: ketamine, tylenol w/ codeine, anabolic steroids, testosterone
drug schedules - schedule 4 - correct answer-low potential for abuse; low level of
dependence
examples:
xanax, Soma, Darvon, Valium, Ambien, Tramadol
drug schedules - schedule 5 - correct answer-very low potential for abuse/dependence
Examples:
Robitussin, Lomotil, Motofen, Lyrica, Parepectolin
ACE inhibitors contraindications - correct answer-African American, 2nd/3rd timester
pregnancy, renal disease
ACEI and ARBs can lead to renal failure in who? - correct answer-Patients w/ bilateral renal
artery stenosis
Alternative treatment strategies for statin intolerant patients - correct answer-ezetimibe,
fibrates, nicotinic acid, bile acid sequestrates
combo therapy with infrequent statin dosing
dietary changes
switching to a different statin
appropriate intervals for medication adjustments - correct answer-4-6 weeks is ideal before
adding another drug to the therapy regimen
Beer's Criteria - correct answer-Criteria for "Potentially Inappropriate Medication Use in
Older Adults"; identifies drugs with a high likelihood of causing adverse effects in older adults
pg. 62 in textbook for table
Beta Blockers Contraindications - correct answer-severe HF, Bradycardia, Advanced Heart
block, Hypotension (persistent), cardiogenic shock
BP meds approved for pregnancy - correct answer-Labetalol and Methyldopa
Carbamazepine drug interactions & dosing considerations - correct answer-narrow
therapeutic dose (toxicity is a risk)
CCB Mech of action - correct answer-Promotes relaxation of peripheral arterioles resulting in
a decreased afterload which reduces cardiac oxygen demand
classes of controlled substances: - correct answer-Anabolic steroids, narcotics, stimulants,
depressants, and hallucinogens
clinical tools for treating hyperlipidemia - correct answer-ASCVD risk category, AHA/ACC,
clinical guidelines
CYP450 inducers and inhibitors - correct answer-inducers:
carbamazepine
phenobarbital
phenytoin
, rifampin
griseofulvin
inhibitors:
cimetidine
ciprofloxacin
erythromycin
all azole antifungals
grapefruit juice
isoniazid
ritonavir protease inhibitors
DEA (Federal Drug Enforcement Administration) - correct answer-regulate drugs and other
substances based on their potential for abuse and dependence
digoxin dosaging adjustments and cautions - correct answer-start low, risk of toxicity,
requires frequent monitoring of serum levels;
do not use w/ quinidine
drug of choice for lowering LDL - correct answer-Statins
drug schedules - schedule 2 - correct answer-combination drugs w/ < 15mg hydrocodone
per dosage unit
High potential for abuse and severe physical/psychological dependence
examples:
Vicodin, cocaine, methamphetamine, methadone, Dilaudid, oxycodone, Meperidine,
Fentanyl, Adderall, Ritalin
drug schedules - schedule 3 - correct answer-drugs w/ <90 mg of codeine per dosage unit
abuse would lead to mod-low physical dependence and high psychological dependence
examples: ketamine, tylenol w/ codeine, anabolic steroids, testosterone
drug schedules - schedule 4 - correct answer-low potential for abuse; low level of
dependence
examples:
xanax, Soma, Darvon, Valium, Ambien, Tramadol
drug schedules - schedule 5 - correct answer-very low potential for abuse/dependence
Examples:
Robitussin, Lomotil, Motofen, Lyrica, Parepectolin
