NURS6203
Advanced Pharmacology
Final Exam Guide
Q&A
2024
, 1. **Multiple Choice:** Which of the following drug classes is known to
have a positive inotropic effect on the heart?
A) ACE inhibitors
B) Beta-blockers
C) Calcium channel blockers
D) Cardiac glycosides
**Correct Answer:** D) Cardiac glycosides
**Rationale:** Cardiac glycosides such as digoxin are known for their
positive inotropic effect on the heart, increasing the strength of cardiac
contractions.
2. **Fill-in-the-Blank:** The mechanism of action of statins involves
inhibition of the enzyme ________, which plays a key role in the
synthesis of cholesterol.
**Correct Answer:** HMG-CoA reductase
**Rationale:** Statins work by inhibiting HMG-CoA reductase, an
enzyme involved in the production of cholesterol in the liver.
3. **True/False:** Nonsteroidal anti-inflammatory drugs (NSAIDs) can
increase the risk of gastrointestinal bleeding due to their effects on
prostaglandin synthesis.
**Correct Answer:** True
**Rationale:** NSAIDs can inhibit prostaglandin synthesis, which can
lead to decreased mucosal protection in the gastrointestinal tract and an
increased risk of bleeding.
Advanced Pharmacology
Final Exam Guide
Q&A
2024
, 1. **Multiple Choice:** Which of the following drug classes is known to
have a positive inotropic effect on the heart?
A) ACE inhibitors
B) Beta-blockers
C) Calcium channel blockers
D) Cardiac glycosides
**Correct Answer:** D) Cardiac glycosides
**Rationale:** Cardiac glycosides such as digoxin are known for their
positive inotropic effect on the heart, increasing the strength of cardiac
contractions.
2. **Fill-in-the-Blank:** The mechanism of action of statins involves
inhibition of the enzyme ________, which plays a key role in the
synthesis of cholesterol.
**Correct Answer:** HMG-CoA reductase
**Rationale:** Statins work by inhibiting HMG-CoA reductase, an
enzyme involved in the production of cholesterol in the liver.
3. **True/False:** Nonsteroidal anti-inflammatory drugs (NSAIDs) can
increase the risk of gastrointestinal bleeding due to their effects on
prostaglandin synthesis.
**Correct Answer:** True
**Rationale:** NSAIDs can inhibit prostaglandin synthesis, which can
lead to decreased mucosal protection in the gastrointestinal tract and an
increased risk of bleeding.
