AAB Hematology Board review questions and answrs(latest upate)

Hemoglobin that has 200 times greater binding capacity for the hemoglobin molecules than oxygen? Carboxyhemoglobin Hemoglobin derivative that cause irreversible changes in the RBC cells Sulfehemoglobin Molecular structure of Hemoglobin S Lysine replaces glutamic acid in the 6th position of the beta chain Lab test to confirm the specific diagnosis of sickle cell anemia? Hemoglobin electrophoresis In Hemoglobin C what replaces glutamic acid? Lysine Which hemoglobin is resistant to alkali denaturation? Hemoglobin F What hemoglobins are differentiated by the Kleihauer-Betke technique? Hemoglobin A 1 from hemoglobin F Order of migration of hemoglobin from fastest to slowest, on cellulose acetate at p H 8.4 A1 F S C The cyanmethemoglobin method measures all hemoglobin except Sulfehemoglobin The cyanmethemoglobin method measures Oxyhemoglobin, methemoglobin, and deoxyhemoglobin Hemolytic anemia Normocytic normochromic anemia The RBCs, hemoglobin, and hematocrit are decreased Indirect bilirubin is increased Myoglobin can be separated from hemoglobin by saturating the specimen with: Ammonium sulfate An increased in the erythrocyte sed rate can be the result of an increase in the quantity of: Fibrinogen Which test is increased in cute infections: Erythrocyte sedimentation rate ESR The following sources of errors will FALSELY elevate the ESR Tilted tube Macrocytes Vibrations from a nearby centrifuge CFS has 285 RBC counted in 5 RBC squares after being diluted in a unoppette 1:100 what is the calculated RBC count: 1,425,000 285 x 100 x10 x 5 = 1,425,000 Lyse resistant RBC detected by automated hematology analyzes are seen in whicH clinical condition? Sickle cell On automated hematology analyzers what ca n affect both, the RBC count and the platelet count Schistocytes On automated hematology analyzers hemoglobin determinations may be falsely elevated due to the presence of the following interfering substances Lipemia A leukocyte count greater than the linearity of the analyzer will falsely elevate which other CBC parameter: Hemoglobin Which reagent is the fixative incorporated in the wright stain Methanol How can the color of wright stained RBC be adjusted? Adjusting the p H of the buffer Malarial parasites in RBC are best demonstrated by which stain? Giemsa The result on a leukemia patient are: NASDA 3 + Nasda with sodium fluoride 1+ AMML In which leukemia are the blasts PAS stain positive A L L What is the last RBC precursor to retain the nucleus before it becomes an erythrocyte Metarubricyte Inclusions that represents a remnant of nuclear DNA in a RBC Howell jolly body RNA remnant in RBC are visualize by which supra vital stain? New methylene blue RBC that contains iron stained granules termed Siderocytes Chronic blood loss can lead to: Iron deficiency anemia Typically seen in the peripheral smear in Megaloblastic anemia Oval macrocytes Decreased platelets Hyper segmented neutrophils What is the most characteristic change seen in the W B C of the Megaloblastic anemia in bone marrow Giant metayelocytes In hereditary elliptocytosis Osmotic fragility and autohemolysis are visually normal Tests associated whit the diagnosis of Paroxysmal nocturnal hemoglobinuria Sugar water test Sucrose hemolysis Acidified serum test What is the most common thalassemia in US Beta thalassemia minor