ILE 1 Exam 1 Questions And Answers 100% Verified Solution

ILE 1 Exam 1 Questions And Answers 100% Verified Solution First-Line Antihypertensive Drugs - ANS-Thiazide Diuretics, ACE inhibitors, ARB's, CCB's Evidence suggests that patients with hypertension live longer as a result of taking - ANS-First Line Agents Thiazide diuretics MOA - ANS-Inhibit NaCl reabsorption in DCT (reduce blood volume) long term vasodilators--> decrease uric aid and calcium excretion Thiazide diuretics side effects - ANS-■ HYPER glycemia (be careful with diabetics) ■ HYPERruricemia (can precipitate a gout attack) ■ HYPERtriglyceremia and hypercholesteremia (check lipid profile) ■ HYPOkalemia (potentiates digoxin toxicity, increases risk of arrhythmias) ■ HYPOnatremia (HOLD diuretic, RESTRICT water intake, REPLACE K+ loss) Adverse effects of Thiazide Diuretics - ANS-dehydration, changes in electrolyte levels, decreased excretion of uric acid can lead to gout Loop diuretics don't decrease excretion of - ANS-Ca++ Calcium Channel Blockers - ANS-n