Basic concepts in clinical pharmacology Exam Questions with 100% Correct Answers Verified | Updated

Basic concepts in clinical pharmacology Exam Questions with 100% Correct Answers Verified | Updated What affects drug absorption? - answer• Solubility • pH of drug (acidic drugs better absorbed in thestomach; alkaline drugs in the intestine) • Molecular weight • Surface area • Contact time • Concentration of the drug on the absorption site • Absorption site (blood flow) • Interactions • Transport systems • Formulation How does the formulation of a drug affect its effect? - answerThe particles have different sizes so will affect pts differently Capsules may be designed to stay intact for some hours which can affect the time between doses and the absorption timing What is volume of distribution? - answerHow well a drug is distributed throughout the body based on the concentration of drug in the blood