BMTCN Chapter 1

Two types of marrow - ANSWER-red and yellow red marrow - ANSWER-thick, blood like material found in flat bones and the ends of long bones; location of blood cell formation yellow marrow - ANSWER-soft, fatty material found in the medullary cavity of long bones Hematopoietic location through lifespan - ANSWER-long bones during childhood; axial skeleton in adulthood Cytokines - ANSWER--small proteins important in cell signaling -immunomodulating agents; may up or down regulate the immune system -act through cell receptors -modulate the balance between humoral and cell-based immune responses -regulate the maturation, growth, and responsiveness of particular cell populations -may enhance/inhabit/interact with other cytokines chemokines - ANSWER--large family of cytokines that direct movement of leukocyte populations, including HSC and HPC -induce migration of leukocytes Myeloid progenitor cells mature into the following: - ANSWER-(a) Megakaryocytes (produce platelets) (b) Erythrocytes (c) Mast cells (d) Myeloblasts Myeloblasts mature into - A