Advanced Pharmacology Final - Practice Quiz with questions and answers

Escitalopram may cause serious, potentially fatal reactions when used with _______________. (select all that apply) - correct answer Duloxetine, amitriptilyne, sertraline, St. John's Wort Mixing two serotonin agents can cause serotonin syndrome. The therapeutic effects of imipramine develop over _____________. - correct answer Several weeks The FDA-approved indications for fluoxetine include: (select all that apply) - correct answer Obsessive compulsive disorder, major depressive disorder, bulimia nervosa Taking food with buspirone alters absorption. - correct answer False May be taken with food to minimize gastric irritation Venlafaxine is extensively metabolized on first pass through the ___________. - correct answer Liver Signs and symptoms of lithium toxicity include: (select all that apply) - correct answer Slurred speech, drowsiness Valproate acid has FDA-approved indications for: (select all that apply) - correct answer Acute mania, simple and complex absence seizures, prevention of migraine headaches Atomoxetine selectively ____________ the presynaptic reuptake of norepinephrine resulting in a(n) ________________ attention span. - correct answer Inhibits, improved Phenelzine does not need to be discontinued several days before elective surgery that requires anesthesia. - correct answer False Bupropion can be used for smoking cessation. - correct answer True Methylphenidate is not effective for narcoleptic patients. - correct answer False Clozapine may cause: (select all that apply) - correct answer Syncope, orthostatic hypotension, cardiac arrest Causes bradycardia which could lead to syncope and cardiac arrest Administering risperidone with levodopa is contraindicated. - correct answer True It decreases the effects of levodopa The ___________ form of ziprasidone is frequently used for control of acutely agitated patients. - correct answer Intramuscular (IM) Anticonvulsants are frequently used as mood stabilizers for the treatment of mania and bipolar spectrum disorders because they: - correct answer Reduce synaptic kindling A patient was started on fluoxetine for depression 3 days ago. She now complains that it "doesn't help" and refuses to take it. Understanding the psychopharmacology, the nurse's best first action is to: - correct answer Discuss with the patient that these types of medications often take several weeks before seeing the results. Which of the following is a common side effect of both first- and second-generation antipsychotic drugs? (select all that apply) - correct answer Extrapyramidal side effects such as pseudo-parkinsonism or acute dystonia, neuroleptic malignant syndrome, excessive sedation A male patient who is taking the second-generation antipsychotic reports to the nurse that he has observed a clear fluid leaking from his right nipple for the past month. The nurse's best initial intervention is: - correct answer Inform the patient that this could be a side effect of the medication The physician discusses the appropriateness of prescribing a serotonin/norepinephrine reuptake inhibitor (SNRI) for a patient. Which of the following medications are in this category? - correct answer Venlafaxine and duloxetine A patient has been prescribed a selective serotonin reuptake inhibitor (SSRI) for depression. The nurse should counsel the patient about which of the following possible side effects, among others? - correct answer Fever, sweating, agitation, rapid heartbeat A nurse counsels a patient who has been prescribed a monoamine oxidase inhibitor (MAOI) to treat depression to avoid foods containing tyramine. Which of the following foods should the patient avoid? (select all that apply) - correct answer Yogurt, tofu, pepperoni A patient with severe kidney disease is started on lithium by a new resident. As the nurse on duty your best initial response would be to: - correct answer Contact the resident to remind him that the client has kidney disease and lithium is contraindicated Which of the following is generally true of medications used to treat anxiety disorders? - correct answer Ju