NR 547 WEEK 8 2024 QUESTIONS AND ANSWERS (VERIFIED) 100% CORRECT | A+GRADE Substance use disorder occurs when: Correct Answer the recurrent use of a substance, such as alcohol or drugs, causes clinically significant impairment -including health problems, disability, or failure to meet responsibilities at home, work, or school Tolerance Correct Answer With repeated ingestion of a drug, the drug shows decreased effect. Increasing doses are required to achieve the effects noted with the original admin istration Dependence Correct Answer State of adaptation produced with repeated administration of certain drugs so that physical symptoms occur when the drug is discontinued abruptly. Addiction Correct Answer A change in behavior caused by biochemical changes in the brain after continued substance use characterized by preoccupation with and repeated use of a substance despite of negative outcomes. Withdrawal Correct Answer Physiological and psychological reactions that occur when the use of a substance is stopped abruptly. Intoxication Correct Answer Condition following the ingestion of a substance resulting in changes in level of consciousness, cognition, perc eption, judgment, and behavior. Bernita is a 64 -year-old who has been using heroin for 6 years. She is currently unemployed and lives with her daughter in the city center. She does not have health insurance. prescribe the proper medication: Methadone Buprenorphine Buprenorphine plus naloxone (Suboxone) Naltrexone Correct Answer Methadone Methadone is a full μ -receptor agonist with a long half -life, which can prevent withdrawal symptoms for 24 hours and provide steady control of cravings througho ut the day. It is only administered in methadone federally regulated opioid treatment programs (OTP). Methadone clinics incorporate psychosocial interventions and require daily attendance for the first several months, so this is a good option for a client that has the flexibility to attend daily meetings. Use of methadone in MAT for opioid use disorder helps extend client survival. When patients stop methadone, they have a high likelihood of relapsing, even 10 years after starting treatment. Antoine is a 3 4-year-old who has been abusing prescription oxycodone. He is employed but is on probation at work for increased absenteeism. He desires MAT but is concerned about his roommates stealing his medication to get high. prescribe the proper medication: Methado ne Buprenorphine Buprenorphine plus naloxone (Suboxone) Naltrexone Correct Answer Buprenorphine plus naloxone (Suboxone) In combination with naloxone (Suboxone ): naloxone is a mu opioid receptor antagonist and can therefore block the effects of buprenorphine; however, because naloxone has poor sublingual bioavailability, it does not interfere with buprenorphine's effects when used properly. Naloxone does have go od parenteral bioavailability; thus, if one tries to administer the buprenorphine/naloxone formulation intravenously, naloxone will prevent any rewarding effects from buprenorphine, making this drug a less desirable street drug. Suboxone is a good option f or a client who may not be able to leave work for medication dosing, as it does not need to be taken under direct observation. Lisa is a 29 -year-old who admits to using "pills, heroin, and booze" regularly. She lives in a rural area and is employed part -
time. She has a history of poor compliance with past treatments. prescribe the proper medication: Methadone Buprenorphine Buprenorphine plus naloxone (Suboxone) Naltrexone Correct Answer Naltrexone Naltrexone blocks mu opioid receptors, preventing exogenous opioids from binding there and thus preventing the pleasurable effects of opioid consumption. This medication also reduces alcohol consumption through modulation of opioid systems, thereby reducing the reinforcing effects of alcohol. For those patients with alcohol use disorder, who have poor adherence to a regimen, and are unable to maintain abstinence, long -acting injection naltrexone (Vivitrol) administered monthly can be efficacious. Miranda is a 20 -year-old who is 18 weeks pregnant and uses heroin. She wants to get clean "for her baby." prescribe the proper medication: Methadone Buprenorphine
time. She has a history of poor compliance with past treatments. prescribe the proper medication: Methadone Buprenorphine Buprenorphine plus naloxone (Suboxone) Naltrexone Correct Answer Naltrexone Naltrexone blocks mu opioid receptors, preventing exogenous opioids from binding there and thus preventing the pleasurable effects of opioid consumption. This medication also reduces alcohol consumption through modulation of opioid systems, thereby reducing the reinforcing effects of alcohol. For those patients with alcohol use disorder, who have poor adherence to a regimen, and are unable to maintain abstinence, long -acting injection naltrexone (Vivitrol) administered monthly can be efficacious. Miranda is a 20 -year-old who is 18 weeks pregnant and uses heroin. She wants to get clean "for her baby." prescribe the proper medication: Methadone Buprenorphine
