Inflammation Process - N5315 Advanced
Pathophysiology
Cellular injury - ANSWhat precipitates the inflammatory process?
Mast cell degranulation, activation of the coagulation cascade, activation of the kinin cascade,
release of chemotactic factors, and the activation of the complement cascade - ANSWhat are
the first 5 steps of the inflammatory process?
Functions include bacterial lysis, vasodilation and increased vascular permeability, triggers mast
cell degranulation, chemotaxis, and opsonization - ANSWhat is the function of complement?
Bradykinin - ANSWhat is kinin turned into?
Pain, chemotaxis, and increased vascular permeability and vasodilation - ANSWhat is
bradykinin responsible for?
Kinin system - ANSWhat system does the coagulation cascade have a role in activating?
Factor XII (Hageman factor) - ANSWhat factor activates kinin?
To form fibrin mesh to stop bleeding and to trap microorganisms - ANSWhat is the function of
the coagulation cascade in the inflammatory process?
Activates complement and kinin system - ANSWhat does the plasmin in the coagulation
cascade do?
Neutrophils, eosinophils and monocytes - ANSWhat do released chemotactic factors attract?
6-8 hours - ANSHow soon do neutrophils show up at the site of injury?
1-7 days - ANSHow soon do monocytes show up at the site of the injury?
Phagocytosis - ANSWhat are neutrophils and monocytes responsible for at the site of injury?
Triggers the release of the acute phase reactants - ANSWhat does the rupture of neutrophils
and monocytes trigger during inflammation process?
Mast cell degranulation - ANSWhat is the most important step of the inflammatory cascade?
Pathophysiology
Cellular injury - ANSWhat precipitates the inflammatory process?
Mast cell degranulation, activation of the coagulation cascade, activation of the kinin cascade,
release of chemotactic factors, and the activation of the complement cascade - ANSWhat are
the first 5 steps of the inflammatory process?
Functions include bacterial lysis, vasodilation and increased vascular permeability, triggers mast
cell degranulation, chemotaxis, and opsonization - ANSWhat is the function of complement?
Bradykinin - ANSWhat is kinin turned into?
Pain, chemotaxis, and increased vascular permeability and vasodilation - ANSWhat is
bradykinin responsible for?
Kinin system - ANSWhat system does the coagulation cascade have a role in activating?
Factor XII (Hageman factor) - ANSWhat factor activates kinin?
To form fibrin mesh to stop bleeding and to trap microorganisms - ANSWhat is the function of
the coagulation cascade in the inflammatory process?
Activates complement and kinin system - ANSWhat does the plasmin in the coagulation
cascade do?
Neutrophils, eosinophils and monocytes - ANSWhat do released chemotactic factors attract?
6-8 hours - ANSHow soon do neutrophils show up at the site of injury?
1-7 days - ANSHow soon do monocytes show up at the site of the injury?
Phagocytosis - ANSWhat are neutrophils and monocytes responsible for at the site of injury?
Triggers the release of the acute phase reactants - ANSWhat does the rupture of neutrophils
and monocytes trigger during inflammation process?
Mast cell degranulation - ANSWhat is the most important step of the inflammatory cascade?
