Molecular Diagnostics Chapter 14 Exam 100% solved

Molecular Diagnostics Chapter 14 Exam 100% solved MHC - answerMajor Histocompatability complex, a set of proteins found on the plasma membranes of cells that help display antigen to T cells. MHC I is found on all cells and displays bits of proteins from within the cell; this allows T cells to monitor cell contents and if abnormal peptides are displayed on the surface, the cell is destroyed by killer T cells. MHC II is found only on macrophages and B cells. This class of MHC allows these cells (known as antigen presenting cells) to display bitts of "eaten" (phagocytosed or internalized) proteins on their surface, allowing the activation of helper Ts --> thus further activating immune response. In humans what is the MHC called? Which chromosome is it located on? - answerHLA, 6 MHC class I HLA type - answerHLA-A, HLA-B, HLA-C, one alpha chain and beta-2 micro globulin MHC class II HLA type - answerHLA-D, two chains one alpha one beta ambiguity - answerrecognition of two or more antigens by the same antibody so the allele cannot be called resolution - answerlevel of detail the allele is observed