Agranulocytosis/Neutropenia/agranulocytosis/leukopenia
acute decrease in the number of WBC in peripheral blood
Causes: treatment with antibiotics, bone marrow transplant, chemo, radiation.
--> can lead to:
-respiratory infection
-ulceration of the mouth
-high fever
-UTI
Anaphylactic reaction
respiratory distress/arrest
sx:
-hives/rash
-difficulty breathing
-dilated pupils
-diaphoresis
-"panic" feeling
-^HR
-respiratory arrest
TX:
--admin epinepherine subcut.
--massage site to ^ absorption rate
--repeat dose q15-20min
--notify MD
Brainpower
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,cytotoxic reaction
allergic reaction where cell death occurs
sx:
-decreased WBC, hematocrit, platelets
-elevated liver enzymes
-decreased renal function
TX:
--notify MD to D/C drug
--rest until allergic response is over
serum sickness
allergic reaction where tissue damage occurs up to 1 week after exposure to a drug.
sx:
-itchy rash
-high fever
-swollen lymph nodes
-swollen joints
-edema of face/limbs
TX:
--notify MD to D/C drug
--comfort measures
delayed allergic reaction
allergic reaction w/
sx:
rash
hives
swollen joints
TX:
--Notify MD to D/C drug
--provide skin care
--comfort measures
--antihistamines/topical corticosteroids
blood dyscrasia
bone marrow suppression caused by meds;
sx:
fever/chills/weakness
sore throat
back pain
dark urine
, decreased H&H
low platelets
low WBC
TX:
--monitor labs
--protective isolation (prevent infection) (neutropenic precautions)
--bleeding precautions
--rest
Hypoglycemia
BG<70
-cold/clammy
-fatigue
-increased HR/BP
-confusion
-severe=seizure/coma
caused by:
--too much insulin
--excessive physical activity
--insufficient food
TX:
assess BG
give snack 15 g carb
severe=glucagon then snack
can also give D50W IV 25-50mL
monitor BG
Normal serum osmolality
275-295
Normal BUN
7-20
Normal creatinine level
women: 0.4-1 mg/dL
men: 0.6-1.2 mg/dL
indicator of kidney function