ASCP Hematology Review Exam Questions And Answers

ASCP Hematology Review Exam Questions And Answers Name the locations of active marrow in adults: - ANS sternum, skull, ribs, pelvis, vertebrae Where does hematopoiesis take place during the first 2 months of gestation? - ANS yolk sac Where does the majority of hematopoiesis take place during the 2nd through 7th month of gestation? - ANS spleen When does the bone marrow take over hematopoiesis? - ANS after birth What are the stages in order of the erythrocyte lineage? - ANS (1)rubriblast, (2)prorubricyte, (3)rubricyte, (4)metarubricyte, (5)reticulocyte, (6)erythrocyte What are the stages in order of the granulocyte (neutrophil, eosinophil, basophil) lineage? - ANS (1)myeloblast, (2)promyelocyte, (3)myelocyte, (4)metamyelocyte, (5)band, (6)segmented (7)eos/baso What are the stages in order of the macrophage lineage? - ANS (1)monoblast, (2)promonocyte, (3)monocyte, (4)macrophage What are the stages in order of the platelet lineage? - ANS (1)megakaryoblast, (2)promegakaryocyte, (3)megakaryocyte, (4)platelet What are the stages in order of the lymphocyte lineage? - ANS (1)lymphoblast, (2)prolymphocyte, (3)lymphocyte Which growth factors stimulate the erythrocyte lineage? - ANS GM-CSF, EPO, IL-3 Which growth factors stimulate the granulocyte lineages? - ANS GM-CSF, IL-3 Which growth factors stimulate the platelet lineage? - ANS GM-CSF, IL-3, TPO Which growth factors stimulate the lymphocyte lineage? - ANS IL-2, IL-4, IL-6, IL-7 Which protein functions in the transport of Fe? - ANS transferrin What is the major storage form of Fe? - ANS ferritin What is the long-term (H20) insoluble Fe storage form called? - ANS hemosiderin Excess Iron is stored where? What does this cause? - ANS tissues and body organs, hemosiderosis, hemochromatosis Porphyrias are attributed to? - ANS excessive formation of porphyrins due to blockages in any enzymatic step in the heme synthesis pathway. Red or port wine colored urine can be seen in which condition related to the build up of heme precursors? - ANS porphyria