AGACNP - ENDOCRINE 2023/2024 already passed

AGACNP - ENDOCRINEWhat are the 3 P's in DM1? polydipsia, polyphagia, polyuria What is the difference between DM1 and DM2? Type 1 is absolute insulin deficiency and Type 2 is a progressive insulin deficiency. DM1 has ketones** DM2 does not Brainpower Read More Previous Play Next Rewind 10 seconds Move forward 10 seconds Unmute 0:00 / 0:15 Full screen Somogyi effect hypoglycemia 0300 followed by rebound hyperglycemia at 0700 Dawn phenomenon an increase in blood glucose in the early morning at 0700, most likely due to increased glucose production in the liver after an overnight fast What is associated with DM2? vaginitis and metabolic syndrome What is metabolic syndrome? Abdominal obesity (>40 in M and >35 in W) high triglycerides (>150) low HDL (<40 in M, <50 in W) hypertension (>135/85) insulin resistance, prothrombotic or proinflammatory states Priority treatment for HHNK? IV fluid hydration (extremely high BGL leads to osmotic diuresis because the extra glucose spills over into the urine bringing water with it) 2. then 15U insulin IV followed by 10U SQ What labs would you expect to see in HHNK? blood glucose 600-1000 serum osmolality >310 What labs would you expect to see in DKA? metabolic acidosis: pH <7.30, HCO3 <22, pCO2 <35 Mainstay treatment of DKA? 1. 1L NS x 1 hour, then NS @ 500cc/hr 2. if BGL >500, 1/2NS after first hour 3. when BGL <250, switch to D51/2NS 4. Insulin 0.1u/kg IV bolus then 0.1/u/kg/hr 5. if BGL not lowered by 10% after first hour, repeat insulin bolus Labs for hyperthyroidism Increased T3 & T4 Decreased TSH Disease associated with hyperthyroidism? Graves disease Medication therapy for hyperthyroidism? PTU, methimazole, lugols, propranolol, thiouril treatment for thyroid storm -High doses of thioamides -Replace fluids