AGACNP - Hematology question n answers graded A+ 2023/2024

AGACNP - Hematology What causes Pernicious anemia? - correct answer a deficiency of intrinsic factor, which results in malabsorption of B12 Neurological symptoms are associated with which type of anemia? - correct answer Pernicious Lymphoma Stage I - correct answer Disease localized to single lymph node or group Lymphoma Stage II - correct answer more than one lymph node group is involved and confined to one side of the diaphragm, such as the lymph nodes of the neck and the tonsils Lymphoma Stage III - correct answer cancer has spread to both sides of the diaphragm Lymphoma Stage IV - correct answer cancer has spread to one or more organs beyond the lymph nodes How is lymphoma diagnosed? - correct answer by biopsy of enlarged lymph nodes Non-Hodgkin's Lymphoma - correct answer cancer of the lymphatic tissues less predictable spread common neoplasm b/t ages 20 and 40 yrs old Hodgkin's lymphoma - correct answer Males; 30's (32) cervical adenopathy spread is predictable Reed-sternberg cells Reed-Sternberg cells - correct answer Hodgkin's lymphoma Leukemia - correct answer cancer of white blood cells neoplasms arising from hematopoietic cells in bone marrow hematopoietic cells - correct answer blood forming stem cells Acute Nonlymphocytic Leukemia (ANL) Acute Myelogenous Leukemia (AML) - correct answer 80% of acute leukemia in adults Acute Lymphocytic Leukemia (ALL) - correct answer Pancytopenia (all labs down) with circulating blasts (hallmark of disease) More difficult to cure in adults than children Chronic Lymphocytic Leukemia (CLL) - correct answer Most common leukemia in adults Lymphocytosis (hallmark of disease) 42,000 WBC Median survival is 10 years An 80-year-old man presents with fatigue, lymphadenopathy, splenomegaly, and isolated lymphocytosis. Suspected leukemia diagnosis? - correct answer Chronic Lymphocytic Leukemia CLL Hallmark - correct answer lymphocytic leukemia Chronic Myelogenous Leukemia (CML) - correct answer PHILADELPHIA chromosome Peripheral blood smear usually distinguishes acute and chronic leukemia but a __________ is required to confirm diagnosis. - correct answer bone marrow aspiration Initiate ____________ to reduce tumor lysis syndrome in high risk patients - correct answer allopurinol