BMTCN question n answers graded A+

BMTCNTypical dose of G-CSF given during mobilization process - correct answer 10 mcg/kg per day Upper dosage limit of G-CSF given during mobilization process - correct answer 32 mcg/kg per day How many doses/days of filgrastim typically given before starting collection? - correct answer 4-5 days What volume of blood is typically processed when collecting from a pediatric donor? - correct answer 200-250 mL/kg What is the typical cut-off age for peripheral stem cell donation? - correct answer 13 y/o How is the success of stem cell procurement measured? - correct answer The number of CD34+ cells obtained What does GM-CSF stand for? - correct answer Granulocyte macrophage colony stimulating factor What is the drug name for GM-CSF - correct answer Sargramostim Why is sargramostim rarely used anymore for mobilization? - correct answer It has lower stem cell yields than other modalities, as well as increased mild and serious adverse events compared to other modalities Primary choice of chemo for multiple myeloma and amyloidosis prior to auto BMT? - correct answer Melphalan What is BEAM? - correct answer Carmustine, etoposide, cytarabine, and melphalan What is the primary conditioning regimen for auto BMT for AML or lymphoma? - correct answer BEAM