lOMoAR cPSD| 784381
Pharm Hesi Drugs Study Guide
Surgical Nursing Development Course
DRUG CLASS MOA SIDE EFFECT/CONTRA NURSING ACTION
NTG antianginals Acute ( translingual, SL, SE: hypotension, tachycardia, syncope -Acute Anginal Attacks:
Nitroglycerine ointment ) and long-term Relief usually occurs within 5
prophylatic ( oral, C: Severe anemia, pericarditis min. Dose may be repeated if
transdermal ) management pain is not relieved in 5–10
of angina pectoris. min. Call health care
vasodilation professional or go to nearest
emergency room if anginal
pain is not relieved by 3
tablets in 15 min.
SL—keep in dark containter
away from moisture, may
loose potency.
montelukast (Singulair) leukotriene receptor allergy, cold and cough SE : -Monitor behavior, may cause
antagonist (anti- remedies Cough, rhinorrhea suicidal thoughts
inflammatory)
bronchodilators , suicidal thoughts, HA insomnia, tremors. -For chronic asthma attack
Decrease inflammatory C: Acute asthma attack
response in chronic asthma
Zileuton (Zyflo) Leukotriene antagonist Inhibits the enzyme 5- Suicidal thoughts, HA insomnia, tremors, -Monitor behavior, may cause
lipoxygenase that catalyzes to arthralgia suicidal thoughts
formation of leukotrienes. -For chronic asthma attack
Result is decreased
inflammatory process that is
part of asthma.
Oxycodone Opioid Binds to opiate receptors in SE: -Assess BP, RR, and HR. Hold
(Percocet) the CNS RR depression, constipation, dizziness if RR < 10 breath/min or
C: Hypersensitivity to bradycarida occus.
acetaminophen/aspirin/ibuprofen
Ondansetron(Zofran) Anti-emetic N/V headache, dizziness, drowsiness, Advise patient to notify health
TORSADE DE POINTE, constipation, care professional immediately
diarrhea, abdominal pain, dry mouth, ↑ liver if symptoms of irregular heart
enzymes., extrapyramidal reactions. beat or involuntary movement
of eyes, face, or limbs occur.
, Metoclopramide antiemetics Blocks dopamine receptors in SE: constipation, diarrhea, - Monitor for neuroleptic
(Reglan) chemoreceptor trigger zone of drowsiness, extrapyramidal malignant syndrome
the CNS. reactions, restlessness, (hyperthermia, muscle rigidity,
Stimulates motility of the altered consciousness,
upper GI tract and accelerates
gastric emptying.
C: Pheochromocytoma irregular pulse or BP,
Parkinson's disease tachycardia, and diaphoresis).
Tx N/V, Decreased - Assess (parkinsonian—
symptoms of gastric stasis. difficulty speaking or
swallowing, loss of balance
control, pill rolling, mask-like
face, shuffling gait, rigidity,
Isoniazid antituberculars First-line therapy of active SE: N+v, hepatitis, peripheral neuropathy, -Do not take with aluminum or
(INH-tyramine) tuberculosis psychosis, fever, visual disturbances antacid, decrease absorption
First-line therapy of active C: Liver disease , hepatitis induce from -Check LFTs (AST, ALT, Alk
tuberculosis isoniazid phosphate)
Bacteriostatic -Drug is hepatoxic
Linezolid anti-infectives Inhibits bacterial protein SE: teeth discoloration, tongue -Take full course of therapy
(Zyvox) synthesis discoloration, bloody diarrhea , HA -May stain teeth
Tx vancomycin- insomnia -Report bloody diarrhea
resistant Enterococcus C: Uncontrolled HTN, pheochromocytoma,
faecium thyrotoxicosis, or concurrent use of
sympathomimetic agents
Baclofen antispasticity agents Treatment of reversible SE: Tinnitus, hypotension seizures - CNS depressant check BP
(Gablofen) spasticity due to multiple C: Epilepsy and RR before meds.
sclerosis or spinal cord MOA inhibitors, antihypertensive -May cause hyperglycemia
lesions
Bulk-forming Work by increasing the amount Bloating, gas, or stomach cramps may occur. Before using this medicine,
of water in the stool, making it consult your doctor or
laxative (Metamucil) softer and easier to pass.
pharmacist if you have:
sudden/unexplained abdomina
l pain, nausea/vomiting, other
symptoms
of appendicitis (e.g., very
tense abdomen, fever, chills),
blockage in the intestines, hole
in the intestines (perforation).
Sucralfate antiulcer agents Short-term management of SE: constipation, diarrhea, dry mouth, - Administer on an empty
duodenal ulcers. hyperglycemia stomach, 1 hr before meals
(Carafate) Aluminum salt of sulfated and at bedtime.
Pharm Hesi Drugs Study Guide
Surgical Nursing Development Course
DRUG CLASS MOA SIDE EFFECT/CONTRA NURSING ACTION
NTG antianginals Acute ( translingual, SL, SE: hypotension, tachycardia, syncope -Acute Anginal Attacks:
Nitroglycerine ointment ) and long-term Relief usually occurs within 5
prophylatic ( oral, C: Severe anemia, pericarditis min. Dose may be repeated if
transdermal ) management pain is not relieved in 5–10
of angina pectoris. min. Call health care
vasodilation professional or go to nearest
emergency room if anginal
pain is not relieved by 3
tablets in 15 min.
SL—keep in dark containter
away from moisture, may
loose potency.
montelukast (Singulair) leukotriene receptor allergy, cold and cough SE : -Monitor behavior, may cause
antagonist (anti- remedies Cough, rhinorrhea suicidal thoughts
inflammatory)
bronchodilators , suicidal thoughts, HA insomnia, tremors. -For chronic asthma attack
Decrease inflammatory C: Acute asthma attack
response in chronic asthma
Zileuton (Zyflo) Leukotriene antagonist Inhibits the enzyme 5- Suicidal thoughts, HA insomnia, tremors, -Monitor behavior, may cause
lipoxygenase that catalyzes to arthralgia suicidal thoughts
formation of leukotrienes. -For chronic asthma attack
Result is decreased
inflammatory process that is
part of asthma.
Oxycodone Opioid Binds to opiate receptors in SE: -Assess BP, RR, and HR. Hold
(Percocet) the CNS RR depression, constipation, dizziness if RR < 10 breath/min or
C: Hypersensitivity to bradycarida occus.
acetaminophen/aspirin/ibuprofen
Ondansetron(Zofran) Anti-emetic N/V headache, dizziness, drowsiness, Advise patient to notify health
TORSADE DE POINTE, constipation, care professional immediately
diarrhea, abdominal pain, dry mouth, ↑ liver if symptoms of irregular heart
enzymes., extrapyramidal reactions. beat or involuntary movement
of eyes, face, or limbs occur.
, Metoclopramide antiemetics Blocks dopamine receptors in SE: constipation, diarrhea, - Monitor for neuroleptic
(Reglan) chemoreceptor trigger zone of drowsiness, extrapyramidal malignant syndrome
the CNS. reactions, restlessness, (hyperthermia, muscle rigidity,
Stimulates motility of the altered consciousness,
upper GI tract and accelerates
gastric emptying.
C: Pheochromocytoma irregular pulse or BP,
Parkinson's disease tachycardia, and diaphoresis).
Tx N/V, Decreased - Assess (parkinsonian—
symptoms of gastric stasis. difficulty speaking or
swallowing, loss of balance
control, pill rolling, mask-like
face, shuffling gait, rigidity,
Isoniazid antituberculars First-line therapy of active SE: N+v, hepatitis, peripheral neuropathy, -Do not take with aluminum or
(INH-tyramine) tuberculosis psychosis, fever, visual disturbances antacid, decrease absorption
First-line therapy of active C: Liver disease , hepatitis induce from -Check LFTs (AST, ALT, Alk
tuberculosis isoniazid phosphate)
Bacteriostatic -Drug is hepatoxic
Linezolid anti-infectives Inhibits bacterial protein SE: teeth discoloration, tongue -Take full course of therapy
(Zyvox) synthesis discoloration, bloody diarrhea , HA -May stain teeth
Tx vancomycin- insomnia -Report bloody diarrhea
resistant Enterococcus C: Uncontrolled HTN, pheochromocytoma,
faecium thyrotoxicosis, or concurrent use of
sympathomimetic agents
Baclofen antispasticity agents Treatment of reversible SE: Tinnitus, hypotension seizures - CNS depressant check BP
(Gablofen) spasticity due to multiple C: Epilepsy and RR before meds.
sclerosis or spinal cord MOA inhibitors, antihypertensive -May cause hyperglycemia
lesions
Bulk-forming Work by increasing the amount Bloating, gas, or stomach cramps may occur. Before using this medicine,
of water in the stool, making it consult your doctor or
laxative (Metamucil) softer and easier to pass.
pharmacist if you have:
sudden/unexplained abdomina
l pain, nausea/vomiting, other
symptoms
of appendicitis (e.g., very
tense abdomen, fever, chills),
blockage in the intestines, hole
in the intestines (perforation).
Sucralfate antiulcer agents Short-term management of SE: constipation, diarrhea, dry mouth, - Administer on an empty
duodenal ulcers. hyperglycemia stomach, 1 hr before meals
(Carafate) Aluminum salt of sulfated and at bedtime.
