NURS6630/NURS 6630 : psychopharmacology Midterm Exam Latest 2021- Walden University

14. First generation Antipsychotics (Typical) bind more tightly to D2 receptors and are not "kicked off" when excess Dopamine is around. This characteristic makes them more likely to cause: - Extrapyramidal Symptoms (dyskinesias and dystonic reactions, tardive dyskinesia, pseudoparkinsonism, akinesia, akathisia, and neuroleptic malignant syndrome) A spasm of the extraocular muscles causing an upward and outward position of the eyes (possible extrapyramidal symptom associated with typical antipscyhotics can occur within hours to days of treatment): - Oculogyric Crisis Acute extrapyramidal symptoms include: - Dystonia, Akathisia, and Pseudoparkinsonism Advanced Neuroleptic Malignant Syndrome can cause: - Rhabdomyolysis Adverse effects of MAOIs include: - Serotonin syndrome and hypertensive crisis All SSRIs but paroxetine (D) are pregnancy category - C Another pathway of the CNS that is rich in Dopamine receptors and is responsible for eating behavior: - Medullary Periventricular Another region of the CNS that is rich in Dopamine receptors and is responsible for initiating the vomiting reflex: - Chemoreceptor trigger zone As a Serotonin Antagonist, this Atypical Antidepressant blocks 5-HT2A and 5-HT3A receptors to increase the amount of Serotonin available to bind to 5-HT1A receptors which are more strongly linked to depression: - mirtazapine