NURS 676 ADVANCED
PHARMACOLOGY FINAL EXAM
REVIEW / QUESTIONS AND
CORRECT ANSWERS 2023/2024
GRADED A+.
1/6
, 1. Why are nitrate-free periods every 24 hours necessary for the patient onnitroglycerin
therapy?: To inhibit the development of tolerance
2. What does a low level of thyroid-stimulating hormone indicate?: Hyper-throidism
3. What would be the best option to treat a newly diagnosed patient with a lowTSH level with?:
Propanolol (Inderal)
4. Spironoaldactone (Aldactone) has what mechanism of action (MOA)?: Al-dosterone
antagonist
5. Heparin exerts its therapeutic action by what?: Upregulating the activity of oneof the body's natural
anticoagulant molecules, antithrombin III
6. What physiologic action happens when the offending drug is administeredduring an
anaphylactic reaction.: Mast cells liberate large doses of histamine.
7. What are two systemic psoriasis medications?: Photo-therapy and topicalcorticosteroids
8. What is the first choice of drug therapy for the majority of patients withuncomplicated
stage I hypertension?: Thiazide diuretics
9. What is the effect of cardiac glycosides?: Digitalis glycosides have a negativechronotropic effect on
the cardiac muscle cells.
10. Amenorrhea is the most common side effect of which birth control med-ication?:
Medroxyprogesterone (Depo-Provera)
11. What is an anti-hypertensive agent which competes with epinephrine foravailable beta-
receptor sites?: Atenolol (Tenormin)
12. What type of action does nitrates have on the body?: Reduction in systemicvenous tone.
13. What is the recommended level of low-density lipoprotein cholesterol(LDL) for patients
with known coronary artery disease?: 100mg/dl or less.
14. What is the MOA of group IV anti-dysrhythmia drugs?: Depressing phase 4depolarization and
lengthening phases 1 and 2 repolarization.
15. Which drug therapy should be used to lower the serum concentration of thyroid hormones
and re-establish eumetabolic state in a patient with Graves'disease?: Anti-thyroid drugs.
16. Which type of diuretic would be used for a stage I hypertension in a patientwith renal
insufficiency?: Loop diuretic.
2/6
PHARMACOLOGY FINAL EXAM
REVIEW / QUESTIONS AND
CORRECT ANSWERS 2023/2024
GRADED A+.
1/6
, 1. Why are nitrate-free periods every 24 hours necessary for the patient onnitroglycerin
therapy?: To inhibit the development of tolerance
2. What does a low level of thyroid-stimulating hormone indicate?: Hyper-throidism
3. What would be the best option to treat a newly diagnosed patient with a lowTSH level with?:
Propanolol (Inderal)
4. Spironoaldactone (Aldactone) has what mechanism of action (MOA)?: Al-dosterone
antagonist
5. Heparin exerts its therapeutic action by what?: Upregulating the activity of oneof the body's natural
anticoagulant molecules, antithrombin III
6. What physiologic action happens when the offending drug is administeredduring an
anaphylactic reaction.: Mast cells liberate large doses of histamine.
7. What are two systemic psoriasis medications?: Photo-therapy and topicalcorticosteroids
8. What is the first choice of drug therapy for the majority of patients withuncomplicated
stage I hypertension?: Thiazide diuretics
9. What is the effect of cardiac glycosides?: Digitalis glycosides have a negativechronotropic effect on
the cardiac muscle cells.
10. Amenorrhea is the most common side effect of which birth control med-ication?:
Medroxyprogesterone (Depo-Provera)
11. What is an anti-hypertensive agent which competes with epinephrine foravailable beta-
receptor sites?: Atenolol (Tenormin)
12. What type of action does nitrates have on the body?: Reduction in systemicvenous tone.
13. What is the recommended level of low-density lipoprotein cholesterol(LDL) for patients
with known coronary artery disease?: 100mg/dl or less.
14. What is the MOA of group IV anti-dysrhythmia drugs?: Depressing phase 4depolarization and
lengthening phases 1 and 2 repolarization.
15. Which drug therapy should be used to lower the serum concentration of thyroid hormones
and re-establish eumetabolic state in a patient with Graves'disease?: Anti-thyroid drugs.
16. Which type of diuretic would be used for a stage I hypertension in a patientwith renal
insufficiency?: Loop diuretic.
2/6
