VTNE: Pharmacology Questions and Answers 100% Pass

Who regulates controlled drugs? The FDA (Food and Drug Administration) and the DEA (Drug Enforcement Administration) C-I Schedule I drugs have the most abuse potential and no current medically acceptable use Marajuana, heroin C-II Schedule II drugs have a high abuse potential and are prone to cause severe dependence Written prescription only (except in emergencies with written script within 72 hrs) No refills Morphine, oxycodone, amphetamines, fentanyl C-III Schedule III drugs have moderate abuse potential with low to moderate risk of dependence (more likely psychological than physical) Ketamine, buprenorphine, anabolic steroids, intermediate-acting barbiturates C-IV Schedule IV drugs have a low abuse potential and low risk of dependence Benzodiazepines (diazepam), long-acting barbiturates (phenobarbital) C-V Schedule V drugs have the lowest risk of abuse or dependence of the scheduled drugs Compounded drug One that has been manipulated in a way that is not provided for in an FDA approved drug label Five "rights" of drug administration Right drug Right amount Right route Right time Right patient Therapeutic index (TI) Comparison between a drug's ability to reach the desired effect and its tendency to produce toxic effects TI = LD50/ED50 The larger the number, the safer the drug