BasicandClinicalPharmacology15thEdition
KatzungTrevorTestBankUpdate2023/2024
TESTBANK Page2of822
WWW.THENURSINGMASTERY.COM
www.stuvia.comBasicandClinicalPharmacology15thEditionKatzungTrevorTestBank
Chapter1.Introduction:TheNatureofDrugs&DrugDevelopment&Regulation
1.Anurseworkinginradiologyadministersiodinetoapatientwhoishavinga
computedtomography(CT)scan.Thenurseworkingontheoncologyunit
administerschemotherapytopatientswhohavecancer.AtthePublicHealth
Department,anurseadministersameasles-mumps-rubella(MMR)vaccineto
a14-month-oldchildasaroutineimmunization.Whichbranchof
pharmacologybestdescribestheactionsofallthreenurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologyisthestudyofthebiologiceffectsofchemicals.Nursesare
involvedwithclinicalpharmacologyorpharmacotherapeutics,whichisa
branchofpharmacologythatdealswiththeusesofdrugstotreat,prevent,
anddiagnosedisease.Theradiologynurseisadministeringadrugtohelp
diagnoseadisease.Theoncologynurseisadministeringadrugtohelptreata
disease.Pharmacoeconomicsincludesanycostsinvolvedindrugtherapy.
Pharmacodynamicsinvolveshowadrugaffectsthebodyand
pharmacokineticsishowthebodyactsonthebody.
2.WheninvolvedinphaseIIIdrugevaluationstudies,whatresponsibilities
wouldthenursehave?
A) Workingwithanimalswhoaregivenexperimentaldrugs
B) Choosingappropriatepatientstobeinvolvedinthedrugstudy
C) Monitoringandobservingpatientscloselyforadverseeffects
D) Conductingresearchtodetermineeffectivenessofthedrug Page3of822
WWW.THENURSINGMASTERY.COM
www.stuvia.comAns:C
Feedback:
PhaseIIIstudiesinvolveuseofadruginavastclinicalpopulationinwhich
patientsareaskedtorecordanysymptomstheyexperiencewhiletakingthe
drugs.Nursesmayberesponsibleforhelpingcollectandanalyzethe
informationtobesharedwiththeFoodandDrugAdministration(FDA)but
wouldnotconductresearchindependentlybecausenursesdonotprescribe
medications.Useofanimalsindrugtestingisdoneinthepreclinicaltrials.
SelectpatientswhoareinvolvedinphaseIIstudiestoparticipateinstudies
wheretheparticipantshavethediseasethedrugisintendedtotreat.These
patientsaremonitoredcloselyfordrugactionandadverseeffects.PhaseI
studiesinvolvehealthyhumanvolunteerswhoareusuallypaidfortheir
participation.Nursesmayobserveforadverseeffectsandtoxicity.
3.Aphysicianhasorderedintramuscular(IM)injectionsofmorphine,a
narcotic,every4hoursasneededforpaininamotorvehicleaccidentvictim.
Thenurseisawarethisdrughasahighabusepotential.Underwhatcategory
wouldmorphinebeclassified?
A) ScheduleI
B) ScheduleII
C) ScheduleIII
D) ScheduleIV
Ans:B
Feedback:
NarcoticswithahighabusepotentialareclassifiedasScheduleIIdrugs
becauseofseveredependenceliability.ScheduleIdrugshavehighabuse
potentialandnoacceptedmedicaluse.ScheduleIIIdrugshavealesser
abusepotentialthanIIandanacceptedmedicaluse.ScheduleIVdrugshave
lowabusepotentialandlimiteddependenceliability. Page4of822
WWW.THENURSINGMASTERY.COM
www.stuvia.com4.Whatconceptisconsideredwhengenericdrugsaresubstitutedforbrand
namedrugs?
A) Bioavailability
B) Criticalconcentration
C) Distribution
D) Half-life
Ans:A
Feedback:
Bioavailabilityistheportionofadoseofadrugthatreachesthesystemic
circulationandisavailabletoactonbodycells.Bindersusedinageneric
drugmaynotbethesameasthoseusedinthebrandnamedrug.Therefore,
thewaythebodybreaksdownandusesthedrugmaydiffer,whichmay
eliminateagenericdrugsubstitution.Criticalconcentrationistheamountof
adrugthatisneededtocauseatherapeuticeffectandshouldnotdiffer
betweengenericandbrandnamemedications.Distributionisthephaseof
pharmacokinetics,whichinvolvesthemovementofadrugtothebodys
tissuesandisthesameingenericandbrandnamedrugs.Adrugshalf-lifeis
thetimeittakesfortheamountofdrugtodecreasetohalfthepeaklevel,
whichshouldnotchangewhensubstitutingagenericmedication.
5.Anurseisassessingthepatientshomemedicationuse.Afterlisteningtothe
patientlistcurrentmedications,thenurseaskswhatpriorityquestion?
A) Doyoutakeanygenericmedications?
B) Areanyofthesemedicationsorphandrugs?
C) Arethesemedicationssafetotakeduringpregnancy?
D) Doyoutakeanyover-the-countermedications?
Ans:D
Feedback:
KatzungTrevorTestBankUpdate2023/2024
TESTBANK Page2of822
WWW.THENURSINGMASTERY.COM
www.stuvia.comBasicandClinicalPharmacology15thEditionKatzungTrevorTestBank
Chapter1.Introduction:TheNatureofDrugs&DrugDevelopment&Regulation
1.Anurseworkinginradiologyadministersiodinetoapatientwhoishavinga
computedtomography(CT)scan.Thenurseworkingontheoncologyunit
administerschemotherapytopatientswhohavecancer.AtthePublicHealth
Department,anurseadministersameasles-mumps-rubella(MMR)vaccineto
a14-month-oldchildasaroutineimmunization.Whichbranchof
pharmacologybestdescribestheactionsofallthreenurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologyisthestudyofthebiologiceffectsofchemicals.Nursesare
involvedwithclinicalpharmacologyorpharmacotherapeutics,whichisa
branchofpharmacologythatdealswiththeusesofdrugstotreat,prevent,
anddiagnosedisease.Theradiologynurseisadministeringadrugtohelp
diagnoseadisease.Theoncologynurseisadministeringadrugtohelptreata
disease.Pharmacoeconomicsincludesanycostsinvolvedindrugtherapy.
Pharmacodynamicsinvolveshowadrugaffectsthebodyand
pharmacokineticsishowthebodyactsonthebody.
2.WheninvolvedinphaseIIIdrugevaluationstudies,whatresponsibilities
wouldthenursehave?
A) Workingwithanimalswhoaregivenexperimentaldrugs
B) Choosingappropriatepatientstobeinvolvedinthedrugstudy
C) Monitoringandobservingpatientscloselyforadverseeffects
D) Conductingresearchtodetermineeffectivenessofthedrug Page3of822
WWW.THENURSINGMASTERY.COM
www.stuvia.comAns:C
Feedback:
PhaseIIIstudiesinvolveuseofadruginavastclinicalpopulationinwhich
patientsareaskedtorecordanysymptomstheyexperiencewhiletakingthe
drugs.Nursesmayberesponsibleforhelpingcollectandanalyzethe
informationtobesharedwiththeFoodandDrugAdministration(FDA)but
wouldnotconductresearchindependentlybecausenursesdonotprescribe
medications.Useofanimalsindrugtestingisdoneinthepreclinicaltrials.
SelectpatientswhoareinvolvedinphaseIIstudiestoparticipateinstudies
wheretheparticipantshavethediseasethedrugisintendedtotreat.These
patientsaremonitoredcloselyfordrugactionandadverseeffects.PhaseI
studiesinvolvehealthyhumanvolunteerswhoareusuallypaidfortheir
participation.Nursesmayobserveforadverseeffectsandtoxicity.
3.Aphysicianhasorderedintramuscular(IM)injectionsofmorphine,a
narcotic,every4hoursasneededforpaininamotorvehicleaccidentvictim.
Thenurseisawarethisdrughasahighabusepotential.Underwhatcategory
wouldmorphinebeclassified?
A) ScheduleI
B) ScheduleII
C) ScheduleIII
D) ScheduleIV
Ans:B
Feedback:
NarcoticswithahighabusepotentialareclassifiedasScheduleIIdrugs
becauseofseveredependenceliability.ScheduleIdrugshavehighabuse
potentialandnoacceptedmedicaluse.ScheduleIIIdrugshavealesser
abusepotentialthanIIandanacceptedmedicaluse.ScheduleIVdrugshave
lowabusepotentialandlimiteddependenceliability. Page4of822
WWW.THENURSINGMASTERY.COM
www.stuvia.com4.Whatconceptisconsideredwhengenericdrugsaresubstitutedforbrand
namedrugs?
A) Bioavailability
B) Criticalconcentration
C) Distribution
D) Half-life
Ans:A
Feedback:
Bioavailabilityistheportionofadoseofadrugthatreachesthesystemic
circulationandisavailabletoactonbodycells.Bindersusedinageneric
drugmaynotbethesameasthoseusedinthebrandnamedrug.Therefore,
thewaythebodybreaksdownandusesthedrugmaydiffer,whichmay
eliminateagenericdrugsubstitution.Criticalconcentrationistheamountof
adrugthatisneededtocauseatherapeuticeffectandshouldnotdiffer
betweengenericandbrandnamemedications.Distributionisthephaseof
pharmacokinetics,whichinvolvesthemovementofadrugtothebodys
tissuesandisthesameingenericandbrandnamedrugs.Adrugshalf-lifeis
thetimeittakesfortheamountofdrugtodecreasetohalfthepeaklevel,
whichshouldnotchangewhensubstitutingagenericmedication.
5.Anurseisassessingthepatientshomemedicationuse.Afterlisteningtothe
patientlistcurrentmedications,thenurseaskswhatpriorityquestion?
A) Doyoutakeanygenericmedications?
B) Areanyofthesemedicationsorphandrugs?
C) Arethesemedicationssafetotakeduringpregnancy?
D) Doyoutakeanyover-the-countermedications?
Ans:D
Feedback:
