ONS ONCC CHEMO RENEWAL EXAM / 60+ QUESTIONS AND CORRECT ANSWERS 2023/2024 / GRADED A+.

ONS ONCC CHEMO RENEWAL EXAM / 60+ QUESTIONS AND CORRECT ANSWERS 2023/2024 / GRADED A+. 2 / 12 1. Neoadjuvant therapy does not increase survival when compared to adjuvanttherapy. It only changes the timing of treatment and can change surgical op-tionsif the tumor isshrunk enough.If this occurs,the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy: ANSW Mainbenefit of neoadjuvant chemotherapy (breast cancer patient) 2. A comprehensive geriatric assessment (CGA) is a multidisciplinary evalua-tion to assess life expectancy and risk of morbidity and mortality in the olderpatient.This assessment tool would evaluate and include the following areas:functional status, socioeconomic issues, psychosocial distress, comorbidi- ties, cognitive function, nutritional status, polypharmacy, and a medication review (NCCN Older Adult Oncology Guidelines, version 1.2015).: ANSW Due to Mrs.Turner's age and comorbidities, her oncologist performs a comprehensive geriatricassessment.You know that this assessment covers all but which of the following: 3. 65: The NCCN Older Adult Oncology Guidelines (version 1.2015) provides in- formation on what is included in a comprehensive geriatric assessment. Currently,more than 60% of cancersin the United States occurin people age and older and as the oncology world ages, nearly half (46%) of cancer survivors are 70 yearsof age or older 4. Two of the agents (docetaxel and carboplatin) that Mrs. Turner will receive are categorized as irritants. Docetaxel can cause a significant reaction if it extravasates. It can lead to edema, erythema, occasional pain and blister formation (ONS Chemo/Bio guidelines, 2014). That is the most likely reason that Mrs.Turner was given a portfor her treatments.Some patients will receivetheir treatments through a peripheral IV without incident. Just because they are intravenous agents does not mean that a port is required and needing a port has nothing to do with her being older in age. Since none of these agentsare vesicants,they likely could have been given safely via peripheral route buthaving a port placed is OK as well.: What is your best explanation for why Mrs. Turner was given a port to receive her chemotherapy? 5. Irrirtants: can cause inflammation, pain, and burning but rarely cause tissue necrosis comparable to a vesicant (unless a large amount or a veryhigh concentration of the irritant is extravasated). 3 / 12 6. Vesicants: can cause blistering and significant pain and tissuedamage and destruction, leading to tissue death. 7. Non-DNA-binding solutions remain in the local area of the extravasation,which improves the possibility of drug deactivation. DNA-binding agents attach to DNA nucleic acids, causing the antagonist to be ingested cellularly, leading to progressive tissue destruction: A further 4 / 12 classification of an antineoplastic agent's potential to cause damage is whether itsmechanism of action includes DNA binding. 8. Bendamustinea Dactinomycin Daunorubicin Doxorubicin Epirubicin Idarubicin Mechlorethamine Mitomycin: DNA Binding Irritants 9. Amsacrine Paclitaxel Vinblastine Vincristine Vindesine Vinorelbine: DNA Nonbinding vessicants 10. Sodium thiosulfate Inject 2 ml of sodium thiosulfate for each milligram ofmechlorethamine extravasated. Inject subcutaneously into extravasation site using a 2