Solutions
Hypersensitivity: Type 1 CORRECT ANSWERS -Mediated IgE
-inflammation due to mast cell degranultion -anaphylactic, asthma, hay fever treatment: epinephrine
Hypersensitivity: Type 2 CORRECT ANSWERS -Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE -macrophages are primary effectors cells involved cause tissue damage or alter function
Hypersensitivity 2 CORRECT ANSWERS -Graves Disease (hyperthyroidism) -
alters function not destroy -blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis -drug allergies -hemolytic anemia
Hypersensitivity: type 3 CORRECT ANSWERS -Not organ specific -antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood or bodily fluids, and the complex is then deposited in the tissues
Hypersensitivity: Type 3 CORRECT ANSWERS -rheumatoid arthritis -Systemic Lupus Erythematosus (SLE) -Raynaud's
Hives (urticaria) CORRECT ANSWERS Hypersensitivity Type 1
First responders to innate the immune system CORRECT ANSWERS Neutrophils Allergic contact dermatitis CORRECT ANSWERS Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: CORRECT ANSWERS -IgG IgM
-macrophages are primary effort cells -
Serum Sickness CORRECT ANSWERS type 3 hypersensitivity
Hypersensitivity IV, CORRECT ANSWERS -is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune CORRECT ANSWERS -diseases in which the body makes antibodies directed against its own tissues
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Primary immunodeficiency CORRECT ANSWERS -Genetic; inherited -result of single gene defects -B and T cell deficiencies
secondary immunodeficiency CORRECT ANSWERS -acquired
Common cause of secondary immunodeficiency CORRECT ANSWERS Malnutrition
Most patients diagnosed with SLE will have a positive ? CORRECT ANSWERS antinuclear antibody (ANA)
SLE (lupus) CORRECT ANSWERS -Facial rash -vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? CORRECT ANSWERS Glomerulonephritis Sjogren's syndrome CORRECT ANSWERS Inflammation in salivary and lacrimal glands
SLE CORRECT ANSWERS Autoantibodies and auto-active t-cells against DNA and nucleoprotein
Sjögren's syndrome immune changes: CORRECT ANSWERS Autoantibodies and auto-reactive t-cells against apoptotic cells
rheumatoid arthritis manifestations: CORRECT ANSWERS Joint inflammation, stiffness, pain, loss of range of motion
Rheumatoid Arthritis immune changes: CORRECT ANSWERS T-cells and B cells
against joint associated antigens
MS manifestations CORRECT ANSWERS Formation of sclerotic plaque in the brain, leads to Muscle weakness and ataxia
MS immune changes CORRECT ANSWERS T-cells against brain antigens
___ measures the average size of RBCs CORRECT ANSWERS MCV
Anemia occur by... CORRECT ANSWERS -impaired RBC production -excessive blood loss
- increased RBC production
microlytic anemia is characterized by hyper chromic RBS: CORRECT ANSWERS
Hereditary spherocytosis
Anemia CORRECT ANSWERS -"without blood"
4.7-6.1mcl CORRECT ANSWERS Normal for men RBC
4.5-5.2mcL CORRECT ANSWERS Normal for women RBC