Maryville NURS 615 Exam 2 | 105 Questions and Answers with complete solution

What blood values should be monitored with carbamazepine (Tegretol)? - CBC test every 3-4 months to monitor for decrease in WBCs, platelets, and trouble with RBC production. What are the pharmacodynamics of carbamazepine (Tegretol)? - - Auto-metabolizes leading to lower serum levels despite compliance. - Half-life 30 hours as single dose, 15 hours when given repeatedly. What are the Black Box Warnings for carbamazepine (Tegretol)? - - Stevens-Johnson Syndrome (SJS) - Toxic Epidermal Necrolysis (TEN) Carbamazepine (Tegretol) is what type of drug? - Anticonvulsant drug What should families be taught regarding the monitoring of seizure activity? - - Prevention of seizures - Patient Safety - Quality of life issues - Do not discontinue medication due to increased risk of seizures What electrolyte imbalance is noted with the administration of topiramate (Topamax)? - Decrease in sodium bicarbonate leading to hyperchloremic metabolic acidosis. What are adverse effects of topiramate (Topamax)? - - Weight loss, especially in higher dose patients - May affect ability to sweat What are pregnancy precautions for valproate (Depakote)? - - Pregnancy Category X - Teratogen (an agent that causes malformation of an embryo)What instructions will you provide to a woman who wants to get pregnant and has a seizure disorder controlled with valproate (Depakote)? - - Pregnant women should be advised to switch to another anticonvulsant during the first trimester, such as levetiracetam (Keppra), then switch back to volproate (Depakote) in the second trimester. - All anticonvulsants for pregnant women should be monitored by a high-risk obstetrician. What are precautions and contraindications for tricyclic antidepressants? - - Caution cardiac disease patients (may act as an antiarrhythmic) - HTN, tachycardia, and convulsions when used with MAOIs