Maryville NURS 615 Pharm Exam 2 | 78 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTION

Carbamazepine (Tegretol) can sometimes show subtherapeutic range due to what? - Carbamazepine auto-induces metabolism, leading to lower levels despite good compliance What are the black box warnings for Carbamazepine? - Dermatologic reactions 1. Steven's Johnson 2. Toxic epidermal necrolysis What lab test should be ordered for patients on Carbamazepine? - CBC every 3-4 months because it can cause decreased WBC, decreased platelets, and trouble with RBC What kind of teaching needs to be done with families of patients who have seizure disorders? - Prevention is important, patient safety is important, Do NOT abruptly stop taking medication. Ethosuximide (Zarontin), an anti-seizure medication can cause what? - Blood dyscrasias Patients taking Topiramate need to be monitored for what electrolyte imbalance? - Decreased sodium bicarb leading to hyperchloremic metabolic acidosis Topiramate treats seizures and what is one common side effect? - Normal side effect is weight loss, especially in higher dose patients A child on Topiramate that wants to play sports should monitor what? - Don't get overheated. Topiramate may affect his ability to sweat in the heat. What should a pregnant patient be told about taking Valproate (Depakote)? - It is a known teratogen and category X medication. It should not be used in the first trimester, it may be restarted in second trimester.What patient population should tricyclic antidepressants be used cautiously in? - Heart Disease patients Phenelzine (Nardil) is a MAOI. What teaching needs to be done with this medication? - He should not use serotonergic drugs like Imitrex. Also, this class of medication interacts with yogurt, sour cream, soy sauce, etc.