Exam 3: Hypothyroidism Questions and Correct Answers Rated A+

Hypothyroidism This is the deficiency of thyroid hormone that causes a general slowing of the metabolic rate. It is more common in women than men Subclinical _____________ hypothyroidism occurs when the TSH is greater than 4.5 mU/L, but the thyroxine (T4) levels are normal AD Overt Patients with ______ hypothyroidism have elevated TSH and decreased thyroxine levels Primary Type of Hypothyroidism This type of hypothyroidism is caused by destruction of thyroid tissue or defective hormone synthesis Secondary Type of Hypothyroidism This type of hypothyroidism is caused by pituitary disease with decreased TSH secretion or hypothalmic dysfunction with decreased thyrotropin-releasing hormone (TRH) secretion Iron Deficiency What is the most common cause of hypothyroidism? Cretinism Type of Hypothyroidism This is hypothyroidism that develops in infancy and is caused by thyroid hormone deficiencies during fetal or early neonatal life. -impaired memory -slowed speech -decreased initiative Clinical Manifestations What are some manifestations of hypothyroidism? Metabolic Clinical Manifestations Weight gain is most likely a result of decreased _____________ rate Contractility Ouput Clinical Manifestations Cardiovascular problems can occur, which are associated with decreased cardiac ______________ and ____________ Myxedema Clinical Manifestations Patients with severe, long-standing hypothyroidism may display ________, which alters the physical appearance of the skin and subcutaneous tissue with puffiness, facial and periorbital edema, and a masklike affect. Myxedema Clinical Manifestations This occurs due to the accumulation of hydrophilic mucopolysaccharides in the dermis and other tissues AD They are attributed to normal aging manifestations Clinical Manifestations In the older adult, typical manifestations such as fatigue, cold and dry skin, hoarseness, hair loss, constipation, and cold intolerance, are difficult to attribute to hypothyroidism. Why is this the case? Myxedema Complications A _________ coma can occur, which is a medical emergency. It is attributed to mental sluggishness, drowsiness, and lethargy. Collapse Complications Cardiovascular ____________ can result from hypoventilation, hyponatremia, hypoglycemia, and lactic acidosis TSH T4 Diagnostic Studies The most reliable laboratory tests for thyroid function are _____ and free ______ TSH Diagnostic Studies Serum _______ levels help determine the cause of hypothyroidism. High Diagnostic Studies Serum TSH levels are ______ when the defect is in the thyroid Low Diagnostic Studies Serum TSH levels are _____ when the defect is in the pituitary or the hypothalamus Antibodies Diagnostic Studies The presence of thyroid ____________ during testing suggests an autoimmune origin