Orthopedic Certification Test questions with correct answers

Cartilage is made of - Answer collagen and protein Joint Cartilage is made of - Answer extracellular matrix and chondrocytes Extracellular matrix contains primarily - Answer type 2, 4, and 6 collagens as well as aggrecan proteoglycans Type 2 collagen is responsible for - Answer protecting the ends of bone within a joint Aggrecan proteoglycan is mainly responsible for - Answer retaining water molecules, allowing resistance to affects of strenuous use of the joint Chondrocytes within joint cartilage is responsible for - Answer the strength and resistance to loading What is the pathophysiology of osteoarthritis? - Answer when cartilage becomes damaged it starts to lose elasticity, making it more susceptible to injury. With increasing stress and wear the bone starts to become affected causing thickening of bone and formation of bone spurs and osteophytes. Abnormal bone formations can break loose with cartilage fragments and float within joint space. Debris cause synovium to mount and inflammatory response to break down cartilaginous debris. What does the inflammatory response during degeneration of cartilage increase? - Answer the breakdown of remaining healthy cartilage, leading to further degeneration