Rau's Respiratory Care Pharmacology Chapter 2 | 38 Questions and Answers(A+ Solution guide)

Agonist - Chemical or drug that binds to a receptor and creates an effect on the body Antagonist - Chemical or drug that binds to a receptor and blocks the receptor site from receiving an agonist Bioavailability - Amount of drug that reaches the systemic circulation Drug administration - Method by which a drug is made available to the body Enteral - Use of the intestines (tablet, capsule, suppository, elixir, suspension) First pass effect - Initial metabolism in the liver of a drug taken orally before the drug reaches systemic circulation Hypersensitivity - Allergic or immune mediated reaction to a drug, which can be serious, requiring airway maintenance or ventilatory assistance Idiosyncratic Effect - Abnormal or unexpected reaction to a drug, other than an allergic reaction, compared with the predicted effect Inhalation - Taking a substance into the body by breathing in (gases, aerosols) local effect - Limited to the area of treatment, I.e. Inhaled drug to treat constricted airway Lung availability/total systemic availability ratio (L/T ratio) - Amount of drug that is made available to the lung out of the total available to the bod